Related Experiment Video
Updated: Jul 5, 2026

Establishment and Characterization of Small Bowel Neuroendocrine Tumor Spheroids
Published on: October 14, 2019
[Primary T-cell lymphoma of the small bowel]
Ali Alzubi1, István Zöllei, László Krenács
1Orosháza Városi Onkormányzat Kórháza Sebészeti Osztály, Orosháza, Hungary.
Abstract:
Primary malignancies in the small intestine are relatively rare. There are no specific methods to find these tumours in early stage. The authors report a case of a primary T-cell lymphoma in the small bowel that caused diagnostic challenges. A 66-year-old woman presenting with abdominal pain and and a palpable mass in the left upper quadrant of her abdomen was admitted into the hospital. Blood tests, endoscopic examinations, ultrasonography and CT scan could not reveal a definitive diagnosis. While a small bowel follow through examination demonstrated an entero-enteral fistula, its exact position could not have been determined. Consequently, an exploratory laparotomy was carried out, and a tumour was found involving the small bowel loops. The involved portion of the small intestine (with the fistula) was resected, and a side-to-side small bowel anastomosis was performed. Histological and immunohistochemical analyses revealed a primary T-cell lymphoma of the small bowel. There was no evidence of metastatic disease at the time of surgery. The patient received adjuvant chemotherapy, but three months later multiple lung metastases were detected. Small bowel malignant tumours cause significant diagnostic difficulties. Therefore, diagnosis and adequate treatment are usually delayed for some weeks. In the future, capsule endoscopy could help in the diagnostic work-up. Nevertheless, surgical exploration and resection of the tumour will be necessary for the correct diagnosis and treatment.
Related Concept Videos
Histology of the Small Intestine
The intestinal lining features transverse folds called circular folds, each housing fingerlike projections known as intestinal villi. These villi are covered by a layer of simple columnar epithelium, also referred to as...
Renewal of Intestinal Stem Cells
Inflammatory Bowel Disease II: Ulcerative Colitis
Inflammatory Bowel Disease II: Crohn's Disease
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by transmural...
Secondary Lymphoid Organs
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
Inflammatory Bowel Disease III: Crohn's Disease

