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Updated: Jul 5, 2026

Germ Cell Transplantation and Testis Tissue Xenografting in Mice
Published on: February 6, 2012
Abstract:
Allotransplantation of vascularized testicle with mild immune suppression was performed at 132 patients with primary hypogonadism associated with androgenic deficient and endocrine form of impotence. This method permits to achieve stable engraftment in early postoperative period at 83% patients. Acute immunologic rejection crisis and secondary wound disruption are the most frequent complications at early postoperative period. The rate of these complications may be reduced with more intensive immune suppression. At the patients with smooth recovery the testosterone level starts to increase in 1 week after allotransplantation and stabilizes during all first year on the level of normal and subnormal parameters.
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