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Updated: Jul 5, 2026

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
Published on: August 25, 2014
[Neuropsychological syndromes of infancy]
Insights
Infants with mild perinatal encephalopathy show distinct left and right brain hemisphere syndromes impacting communication and behavior. These syndromes may stem from underlying global neurodynamics disturbances.
Area of Science:
- Neuropsychology
- Developmental Pediatrics
- Neuroscience
Context:
- Study investigated 77 infants with mild perinatal encephalopathy.
- Focused on infants with dysfunction in one brain hemisphere.
- Utilized O.V. Bazhenova's (1986) method for assessing neuropsychological syndromes.
Purpose:
- To characterize and differentiate neuropsychological syndromes in infants with unilateral brain hemisphere dysfunction.
- To explore the relationship between specific hemispheric syndromes and developmental patterns.
- To identify potential underlying neurodynamic disturbances.
Summary:
- Right hemisphere syndrome: reduced reactivity, early emotional communication, advanced complex communication, and object-oriented interests.
- Left hemisphere syndrome: high reactivity, generalized activity, weak regulation, delayed complex communication, but strong early emotional communication.
- Syndrome exacerbation differs: left-hemisphere issues worsen with overstimulation, right-hemisphere with understimulation.
Impact:
- Provides distinct profiles for left and right hemisphere syndromes in infants with perinatal encephalopathy.
- Suggests global neurodynamics disturbances as a potential etiological factor.
- Informs targeted interventions for infants with specific hemispheric impairments.
Abstract:
Neuropsychological syndromes of infancy, using a method by O.V. Bazhenova (1986), were studied in 77 infants with mild perinatal encephalopathy and dysfunction of one brain hemisphere. The right hemisphere syndrome is characterized by the reduction of reactivity and immediate emotional communication, accelerated development of complicated modes of communication and interest in item operations. The left hemisphere syndrome is characterized by the high reactivity to stimulation with generalized activity and weakness of regulation processes, retardation of complicated modes of communication and item operations but the well development of immediate emotional communication. These peculiarities in infants with the left hemisphere syndrome aggravate in the excess of impressions and stimulation and in those with the right hemisphere syndrome - in their limitation. It is suggested that the syndromes are underlie by disturbances of global neurodynamics.
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