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Reproducible Motor Deficit Following Aortic Occlusion in a Rat Model Of Spinal Cord Ischemia
Published on: July 22, 2017
Acquired ocular motor apraxia after aortic surgery
Robert Donald Yee1, Valerie Ann Purvin
1Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, USA.
Transactions of the American Ophthalmological Society
|April 23, 2008
Summary
This study describes acquired ocular motor apraxia, a rare condition causing impaired eye movements after aortic surgery. The findings suggest potential brainstem or frontal lobe pathway damage.
Area of Science:
- Neuroscience
- Ophthalmology
- Cardiovascular Surgery
Background:
- Acquired ocular motor apraxia is a rare neurological disorder affecting voluntary eye movements.
- Aortic root and arch surgeries are complex procedures with potential neurological complications.
Observation:
- Three patients developed ophthalmoplegia following aortic surgery.
- Neuro-ophthalmic examination revealed absent or impaired volitional and reflex saccades.
- Smooth pursuit and vestibulo-ocular response (VOR) remained intact in most patients.
Findings:
- Patients exhibited profound deficits in horizontal and vertical saccades.
- Magnetic resonance imaging (MRI) showed lesions in the brainstem or cerebrum in one patient.
- The syndrome appears distinct, with pathophysiology potentially linked to brainstem or frontal eye field pathways.
Implications:
- This case series highlights a unique syndrome of acquired ocular motor apraxia post-aortic surgery.
- Understanding the neural pathways of saccade generation is crucial for diagnosing and managing such cases.
- Further research is needed to elucidate the exact pathophysiology and optimize patient outcomes.
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