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Updated: Jul 5, 2026

Multiplexed Fluorescent Immunohistochemical Staining of Four Endometrial Immune Cell Types in Recurrent Miscarriage
Published on: August 4, 2021
[Mourning, coping and subjective attribution after early miscarriage]
Annekathrin Bergner1, Reinhard Beyer, Burghard F Klapp
1Medizinische Klinik mit Schwerpunkt Psychosomatik und Psychotherapie, Charité-Universitätsmedizin Berlin.
A few weeks after miscarriage 232 women were questioned with standardized questionnaires and symptom scales about the way in which they coped with an early miscarriage (up to the 16th week of gestation) about mourning processes and subjective attribution as well as anamnestic and psychosocial characteristics. Seven and fourteen months after pregnancy loss and if necessary in the first trimester of a following pregnancy the psychological symptoms of the women (fear and depressive symptoms) were evaluated. A few weeks after miscarriage we found with main component analysis three patterns of coping. The pattern of "depressive coping" could be diagnosed as a predictor of increased depression seven months after the miscarriage and in a new pregnancy. Depressive pathology in a new pregnancy of the women with early pregnancy loss can be predicted also over the pattern of "anxious grieving". On the other hand, the pattern of "active coping" is associated with lower state anxiety in a new pregnancy. Lack of perceived partner support and past divorces or separations are risk factors for increased fears in a new pregnancy. These results suggest that women who have had an early miscarriage especially if they have maladaptive coping patterns and psychosocial risk factor for maladjustment need prevention of psychological disturbances with an integrated psychosomatic concept.
A few weeks after miscarriage 232 women were questioned with standardized questionnaires and symptom scales about the way in which they coped with an early miscarriage (up to the 16th week of gestation) about mourning processes and subjective attribution as well as anamnestic and psychosocial characteristics. Seven and fourteen months after pregnancy loss and if necessary in the first trimester of a following pregnancy the psychological symptoms of the women (fear and depressive symptoms) were evaluated. A few weeks after miscarriage we found with main component analysis three patterns of coping. The pattern of "depressive coping" could be diagnosed as a predictor of increased depression seven months after the miscarriage and in a new pregnancy. Depressive pathology in a new pregnancy of the women with early pregnancy loss can be predicted also over the pattern of "anxious grieving". On the other hand, the pattern of "active coping" is associated with lower state anxiety in a new pregnancy. Lack of perceived partner support and past divorces or separations are risk factors for increased fears in a new pregnancy. These results suggest that women who have had an early miscarriage especially if they have maladaptive coping patterns and psychosocial risk factor for maladjustment need prevention of psychological disturbances with an integrated psychosomatic concept.
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