Liposome vectors for in vivo gene delivery

Gene therapy with nonviral, cationic liposome-based vectors has demonstrated promising results in a variety of in vivo models and some clinical trials. In contrast to viral vectors, cationic liposome-based vectors usually induce just mild inflammatory reactions, making them suitable for repeated injections in animals. This unit describes the preparation and delivery of two liposome-based vectors Gene therapy with nonviral, cationic liposome-based vectors has demonstrated promising results in a variety of in vivo models.