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Related Concept Videos

Proteomics01:33

Proteomics

A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term proteomics...
Peptide Identification Using Tandem Mass Spectrometry01:33

Peptide Identification Using Tandem Mass Spectrometry

Tandem mass spectrometry, also known as MS/MS or MS2, is an analytical technique that employs two mass analyzers. Essentially it is a series of mass spectrometers that helps isolate a particular biomolecule and then helps study its chemical properties.
This technique helps gather information regarding the protein from which the peptide was obtained and to study the peptides’ amino acid sequence. Identifying peptides from a complex mixture is an important component of the growing field of...
Rapid Identification of Pathogens01:25

Rapid Identification of Pathogens

MALDI-TOF MS has transformed clinical microbiology by offering a rapid and reliable method for pathogen identification. The traditional approach to microbial identification typically involves time-consuming culture techniques and biochemical tests, which can delay the initiation of appropriate antimicrobial therapy. MALDI-TOF MS avoids these delays by using characteristic ribosomal protein mass patterns of microbial cells, enabling accurate species-level identification within minutes.Principle...

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Related Experiment Video

Updated: Jul 5, 2026

Mass Spectrometry-Based Proteomics Analyses Using the OpenProt Database to Unveil Novel Proteins Translated from Non-Canonical Open Reading Frames
07:38

Mass Spectrometry-Based Proteomics Analyses Using the OpenProt Database to Unveil Novel Proteins Translated from Non-Canonical Open Reading Frames

Published on: April 11, 2019

Using the Proteomics Identifications Database (PRIDE).

Lennart Martens1, Phil Jones, Richard Côté

  • 1EMBL-EBI, Wellcome Trust Genome Campus, Hinxton, Cambridge.

Current Protocols in Bioinformatics
|April 23, 2008
PubMed
Summary
This summary is machine-generated.

The Proteomics Identifications Database (PRIDE) is a public repository for mass spectrometry proteomics data. It offers tools for data submission, analysis, and secure, confidential peer-review access.

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Navigating the Mass Spectrometry-Based Proteomic Data Using Free Computational Tools

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TMT Sample Preparation for Proteomics Facility Submission and Subsequent Data Analysis
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TMT Sample Preparation for Proteomics Facility Submission and Subsequent Data Analysis

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Related Experiment Videos

Last Updated: Jul 5, 2026

Mass Spectrometry-Based Proteomics Analyses Using the OpenProt Database to Unveil Novel Proteins Translated from Non-Canonical Open Reading Frames
07:38

Mass Spectrometry-Based Proteomics Analyses Using the OpenProt Database to Unveil Novel Proteins Translated from Non-Canonical Open Reading Frames

Published on: April 11, 2019

Navigating the Mass Spectrometry-Based Proteomic Data Using Free Computational Tools
07:01

Navigating the Mass Spectrometry-Based Proteomic Data Using Free Computational Tools

Published on: August 19, 2025

TMT Sample Preparation for Proteomics Facility Submission and Subsequent Data Analysis
07:44

TMT Sample Preparation for Proteomics Facility Submission and Subsequent Data Analysis

Published on: June 8, 2020

Area of Science:

  • Bioinformatics
  • Proteomics Data Management

Background:

  • Mass spectrometry-based proteomics generates large, complex datasets.
  • Effective data storage, dissemination, and analysis are crucial for scientific reproducibility.
  • Public repositories are essential for sharing and validating proteomics findings.

Purpose of the Study:

  • To describe the functionality of the Proteomics Identifications Database (PRIDE).
  • To detail data submission, querying, viewing, and analysis capabilities.
  • To highlight PRIDE's access control for confidential peer-review.

Main Methods:

  • Description of the PRIDE database architecture and web interface.
  • Explanation of metadata handling and data submission protocols.
  • Overview of search, exploration, and comparison functionalities.

Main Results:

  • PRIDE accommodates detailed metadata for proteomics datasets.
  • A web interface allows querying, exploration, viewing, and downloading of data.
  • An access control mechanism supports confidential peer-review of manuscript-related data.

Conclusions:

  • PRIDE serves as a comprehensive public repository for proteomics data.
  • The database facilitates data sharing, analysis, and secure peer-review.
  • PRIDE enhances the transparency and reproducibility of proteomics research.