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Related Concept Videos

Nucleic acids02:43

Nucleic acids

Nucleic acids are the most important macromolecules for the continuity of life. They carry the cell's genetic blueprint and carry instructions for its functioning.
DNA and RNA
The two main types of nucleic acids are deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). DNA is the genetic material in all living organisms, ranging from single-celled bacteria to multicellular mammals. It is in the nucleus of eukaryotes and in the organelles, chloroplasts, and mitochondria. In prokaryotes, the...
Nucleic Acids02:43

Nucleic Acids

Nucleic acids are the most important macromolecules for the continuity of life. They carry the cell's genetic blueprint and carry instructions for its functioning.
DNA and RNA
The two main types of nucleic acids are deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). DNA is the genetic material in all living organisms, ranging from single-celled bacteria to multicellular mammals. It is in the nucleus of eukaryotes and in the organelles, chloroplasts, and mitochondria. In prokaryotes, the...
Nucleic Acids02:43

Nucleic Acids

Nucleic acids are the most important macromolecules for the continuity of life. They carry the cell's genetic blueprint and carry instructions for its functioning.
DNA and RNA
The two main types of nucleic acids are deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). DNA is the genetic material in all living organisms, ranging from single-celled bacteria to multicellular mammals. It is in the nucleus of eukaryotes and in the organelles, chloroplasts, and mitochondria. In prokaryotes, the...
Nucleic Acids02:43

Nucleic Acids

Nucleic acids are the most important macromolecules for the continuity of life. They carry the cell's genetic blueprint and carry instructions for its functioning.
DNA and RNA
The two main types of nucleic acids are deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). DNA is the genetic material in all living organisms, ranging from single-celled bacteria to multicellular mammals. It is in the nucleus of eukaryotes and in the organelles, chloroplasts, and mitochondria. In prokaryotes, the...
Nucleic Acids and Nucleotides01:20

Nucleic Acids and Nucleotides

Nucleic acids are the most important macromolecules for the continuity of life. They carry the cell's genetic blueprint and have instructions for its functioning. The two main types of nucleic acids are deoxyribonucleic acid (DNA) and ribonucleic acid (RNA).
Deoxyribonucleic Acid (DNA)
DNA is the genetic material in all living organisms, ranging from single-celled bacteria to multicellular mammals. It is in the nucleus of eukaryotes and the organelles such as chloroplasts and mitochondria. In...
Nucleic Acid Structure01:25

Nucleic Acid Structure

The pentose sugar in DNA is deoxyribose, while in RNA the pentose sugar is ribose. The difference between the sugars is the presence of the hydroxyl group on the ribose's second carbon and a hydrogen on the deoxyribose's second carbon. The phosphate residue attaches to the hydroxyl group of the 5′ carbon of one sugar and the hydroxyl group of the 3′ carbon of the sugar of the next nucleotide, which forms  a 5′ to 3′ phosphodiester linkage.
DNA Structure
DNA has a double-helix structure. The...

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Updated: Jul 5, 2026

A Polyaniline-based Sensor of Nucleic Acids
07:58

A Polyaniline-based Sensor of Nucleic Acids

Published on: November 1, 2016

Characteristics of nucleic acids.

D E Bergstrom1

  • 1Purdue University, West Lafayette, USA.

Current Protocols in Nucleic Acid Chemistry
|April 23, 2008
PubMed
Summary

This guide details DNA structures, including A-, B-, and Z-DNA, and their nucleoside/nucleotide building blocks. It covers essential properties, chemical structures, stereochemistry, and base pairing for understanding DNA

Area of Science:

  • Molecular Biology
  • Biochemistry
  • Structural Biology

Background:

  • DNA exists in various helical forms beyond the canonical Watson-Crick model.
  • Understanding DNA structure is fundamental to molecular biology and genetics.
  • Nucleoside and nucleotide properties dictate DNA's structural and functional characteristics.

Purpose of the Study:

  • To compile essential information on DNA constituents and structures.
  • To provide a reference for A-, B-, and Z-DNA forms.
  • To elucidate the chemical and stereochemical basis of DNA structure and base pairing.

Main Methods:

  • Compilation of data from Current Protocols in Molecular Biology.
  • Presentation of experimentally useful properties of nucleoside/nucleotide building blocks.

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Using Modified Synthetic Oligonucleotides to Assay Nucleic Acid-Metabolizing Enzymes

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Last Updated: Jul 5, 2026

A Polyaniline-based Sensor of Nucleic Acids
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Analyzing and Building Nucleic Acid Structures with 3DNA
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Analyzing and Building Nucleic Acid Structures with 3DNA

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  • Detailed illustration of nucleoside chemical structures and nucleotide stereochemistry.

    • Main Results:

    • Characterization of major nucleoside/nucleotide constituents for A-, B-, and Z-DNA.
    • Detailed figures and tables on nucleoside structures and nucleotide stereochemistry.
    • Explanation of base pairing, including alternative (non-Watson-Crick) interactions.
    • Description of the three principal DNA helix structures: A-, B-, and Z-DNA.

    Conclusions:

    • The provided information serves as a comprehensive resource for DNA structural studies.
    • Understanding nucleoside/nucleotide properties is key to comprehending DNA secondary structure.
    • This compilation facilitates research into the diverse structural forms of DNA.