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Nucleic Acids and Nucleotides01:20

Nucleic Acids and Nucleotides

Nucleic acids are the most important macromolecules for the continuity of life. They carry the cell's genetic blueprint and have instructions for its functioning. The two main types of nucleic acids are deoxyribonucleic acid (DNA) and ribonucleic acid (RNA).
Deoxyribonucleic Acid (DNA)
DNA is the genetic material in all living organisms, ranging from single-celled bacteria to multicellular mammals. It is in the nucleus of eukaryotes and the organelles such as chloroplasts and mitochondria. In...
Antiviral Nucleoside Inhibitors01:22

Antiviral Nucleoside Inhibitors

Antiviral Nucleoside InhibitorsAntiviral nucleoside inhibitors are structural analogs of natural nucleosides that interfere with viral DNA or RNA synthesis. These compounds selectively target viral polymerases due to their resemblance to host nucleosides, thereby disrupting viral genome replication.Mechanism of Acyclovir ActionAcyclovir is a guanosine analog with a three-carbon acyclic side chain. It selectively targets herpes simplex virus type 1 (HSV-1), herpes simplex virus type 2 (HSV-2),...
Nucleic acids02:43

Nucleic acids

Nucleic acids are the most important macromolecules for the continuity of life. They carry the cell's genetic blueprint and carry instructions for its functioning.
DNA and RNA
The two main types of nucleic acids are deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). DNA is the genetic material in all living organisms, ranging from single-celled bacteria to multicellular mammals. It is in the nucleus of eukaryotes and in the organelles, chloroplasts, and mitochondria. In prokaryotes, the...
Nucleic Acids02:43

Nucleic Acids

Nucleic acids are the most important macromolecules for the continuity of life. They carry the cell's genetic blueprint and carry instructions for its functioning.
DNA and RNA
The two main types of nucleic acids are deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). DNA is the genetic material in all living organisms, ranging from single-celled bacteria to multicellular mammals. It is in the nucleus of eukaryotes and in the organelles, chloroplasts, and mitochondria. In prokaryotes, the...
Nucleic Acids02:43

Nucleic Acids

Nucleic acids are the most important macromolecules for the continuity of life. They carry the cell's genetic blueprint and carry instructions for its functioning.
DNA and RNA
The two main types of nucleic acids are deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). DNA is the genetic material in all living organisms, ranging from single-celled bacteria to multicellular mammals. It is in the nucleus of eukaryotes and in the organelles, chloroplasts, and mitochondria. In prokaryotes, the...
Nucleic Acids02:43

Nucleic Acids

Nucleic acids are the most important macromolecules for the continuity of life. They carry the cell's genetic blueprint and carry instructions for its functioning.
DNA and RNA
The two main types of nucleic acids are deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). DNA is the genetic material in all living organisms, ranging from single-celled bacteria to multicellular mammals. It is in the nucleus of eukaryotes and in the organelles, chloroplasts, and mitochondria. In prokaryotes, the...

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Updated: Jul 5, 2026

Nucleoside Triphosphates - From Synthesis to Biochemical Characterization
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Nucleoside Triphosphates - From Synthesis to Biochemical Characterization

Published on: April 3, 2014

Nucleoside and nucleotide nomenclature.

J A Secrist1

  • 1Southern Research Institute, Birmingham, Alabama, USA.

Current Protocols in Nucleic Acid Chemistry
|April 23, 2008
PubMed
Summary

This document outlines the evolving nomenclature for nucleosides, nucleotides, and nucleic acids. It references official guidelines from IUPAC/IUBMB and emerging scientific usage for clarity in molecular biology research.

Area of Science:

  • Biochemistry
  • Molecular Biology
  • Chemical Nomenclature

Background:

  • Current nomenclature for nucleosides, nucleotides, and nucleic acids is a blend of common names, official IUPAC/IUBMB guidelines, and evolving scientific usage.
  • A working group was established in 1998 by the International Union of Biochemistry and Molecular Biology (IUBMB) to revise nucleotide and oligonucleotide nomenclature.

Purpose of the Study:

  • To provide essential references for understanding current and evolving nomenclature in nucleic acid chemistry.
  • To guide researchers to relevant guidelines and literature-based nomenclature developments.

Main Methods:

  • Review of existing nomenclature guidelines from official bodies like IUPAC and IUBMB.
  • Compilation of references to peer-reviewed publications showcasing evolving scientific usage.

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Regioselective O-Glycosylation of Nucleosides via the Temporary 2',3'-Diol Protection by a Boronic Ester for the Synthesis of Disaccharide Nucleosides

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Plant Sample Preparation for Nucleoside/Nucleotide Content Measurement with An HPLC-MS/MS
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Nucleoside Triphosphates - From Synthesis to Biochemical Characterization
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Regioselective O-Glycosylation of Nucleosides via the Temporary 2',3'-Diol Protection by a Boronic Ester for the Synthesis of Disaccharide Nucleosides
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Plant Sample Preparation for Nucleoside/Nucleotide Content Measurement with An HPLC-MS/MS

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  • Inclusion of expert commentary and suggestions where appropriate.

    • Main Results:

    • The appendix serves as a curated resource for nomenclature in nucleosides, nucleotides, and nucleic acids.
    • It directs readers to established guidelines and emerging trends in scientific naming conventions.

    Conclusions:

    • Accurate and consistent nomenclature is crucial for clear scientific communication in molecular biology.
    • This resource facilitates adherence to both established and developing standards for naming nucleic acid components.