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NMR determination of oligonucleotide structure.

T L James1

  • 1University of California, San Francisco, California, USA.

Current Protocols in Nucleic Acid Chemistry
|April 23, 2008
PubMed
Summary

Nuclear Magnetic Resonance (NMR) spectroscopy is a powerful tool for determining oligonucleotide structure. This unit details NMR methods, including spectral properties, restraint acquisition, structure refinement, and quality assessment, along with relevant software.

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