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NMR determination of oligonucleotide structure
1University of California, San Francisco, California, USA.
Current Protocols in Nucleic Acid Chemistry
|April 23, 2008
Abstract:
This unit provides an overview of the use of NMR to determine oligonucleotide structure. It covers basic NMR spectral properties, acquisition of interproton distance restraints and torsion angle restraints, structure refinement, assessment of the quality of the structure obtained. Software programs used in the process are also described.
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