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Recent advances in RNA structure determination by NMR

M Hennig1, J R Williamson, A S Brodsky

  • 1The Scripps Research Institute, La Jolla, California, USA.

Current Protocols in Nucleic Acid Chemistry
|April 23, 2008
PubMed

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Nuclear magnetic resonance (NMR) spectroscopy is a very valuable analytical technique for researchers. It has been used for more than 50 years as an analytical tool. F. Bloch and E. Purcell formulated NMR in 1946 and won the 1952 Nobel Prize in Physics  for their work. Biological macromolecules such as proteins, nucleic acids, lipids, and organic molecules including pharmaceutical compounds, can be studied using this versatile tool that exploits the magnetic properties of certain nuclei.
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