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Updated: Jul 5, 2026

A Protocol for Computer-Based Protein Structure and Function Prediction
Published on: November 3, 2011
Protein secondary structure prediction
S R Krystek1, W J Metzler, J Novotny
1Bristol-Myers Squibb Pharmaceutical Research Institute, Princeton, New Jersey, USA.
Abstract:
This unit describes procedures developed for predicting protein structure from the amino acid sequence. The first of the four sections is an overview and brief history of structure prediction schemes. The second section describes four distinct prediction schemes, with emphasis on their differences. In the third part each prediction scheme is used to evaluate three proteins that have different folding patterns. The final section is a comparison of the prediction results and suggestions for secondary structure prediction.
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