Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Protein Families02:47

Protein Families

Protein families are groups of homologous proteins; that is, they have similarities in amino acid sequences and three-dimensional structures. Protein families usually occur because of gene duplication, where an additional copy of a gene is inserted into the genome of an organism.   Mutations that change the amino acids but still allow the protein to be properly synthesized, will lead to new protein family members.   If these new proteins contain similar amino acids in key locations, protein...
Protein and Protein Structure02:15

Protein and Protein Structure

Proteins are one of the most abundant organic molecules in living systems and have the most diverse range of functions of all macromolecules. Proteins may be structural, regulatory, contractile, or protective. They may serve in transport, storage, or membranes; or they may be toxins or enzymes. Their structures, like their functions, vary greatly. They are all, however, amino acid polymers arranged in a linear sequence.
A protein's shape is critical to its function. For example, an enzyme can...
Protein Organization01:24

Protein Organization

Proteins are polymers of amino acid residues. They are versatile and responsible for different cellular functions, including DNA replication, molecular transport, catalysis, and structural support. Proteins have a hierarchical structure comprising at least three levels of organization: primary, secondary, and tertiary structure. Some large proteins have a quaternary structure where individual protein subunits are linked together.
The primary structure of a protein is its amino acid sequence.
Protein Organization01:13

Protein Organization

Overview
Protein Organization01:13

Protein Organization

Overview
Protein Organization01:24

Protein Organization

Proteins are polymers of amino acid residues. They are versatile and responsible for different cellular functions, including DNA replication, molecular transport, catalysis, and structural support. Proteins have a hierarchical structure comprising at least three levels of organization: primary, secondary, and tertiary structure. Some large proteins have a quaternary structure where individual protein subunits are linked together.
The primary structure of a protein is its amino acid sequence.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Unravelling Ovarian Cancer: an analysis of the Influence of LRP1 and PAI1 Genetic Variations.

Biochemical genetics·2026
Same author

Genome-Edited Maize Expressing Two Native Genes Confers Broad-Spectrum Resistance to Northern Corn Leaf Blight.

Molecular plant pathology·2026
Same author

Interplay between NOD1 polymorphisms and gene expression in the pathogenesis of gallstone disease.

Molecular biology reports·2026
Same author

Genetic impact of copy number variations on congenital heart defects: Current insights and future directions.

Global medical genetics·2025
Same author

Optimizing the strain engineering process for industrial-scale production of bio-based molecules.

Journal of industrial microbiology & biotechnology·2023
Same author

Author Correction: Deep mutational scanning of essential bacterial proteins can guide antibiotic development.

Nature communications·2023

Related Experiment Video

Updated: Jul 5, 2026

An Integrated Approach for Microprotein Identification and Sequence Analysis
09:37

An Integrated Approach for Microprotein Identification and Sequence Analysis

Published on: July 12, 2022

Basic protein sequence analysis.

Nandini Krishnamurthy1, Kimmen V Sjölander1

  • 1University of California, Berkeley, California.

Current Protocols in Protein Science
|April 23, 2008
PubMed
Summary

Predicting protein molecular function is crucial in genomics. This study offers accessible web-based tools for domain, localization, and motif detection, integrating results for enhanced analysis.

Area of Science:

  • Bioinformatics
  • Computational Biology
  • Genomics

Background:

  • Accurate prediction of protein molecular function is essential in the genomics era.
  • Numerous sequence analysis tools exist, but integrating their results can be challenging.

Purpose of the Study:

  • To provide accessible protocols for key protein analysis tasks.
  • To develop a strategy for integrating results from different analysis tools.

Main Methods:

  • Selection of primary protocols for domain detection, subcellular localization, and motif detection.
  • Development of a strategy for combining results from various computational tools.
  • Utilizing publicly available web servers and databases.

Main Results:

More Related Videos

Investigating Protein Sequence-structure-dynamics Relationships with Bio3D-web
09:51

Investigating Protein Sequence-structure-dynamics Relationships with Bio3D-web

Published on: July 16, 2017

Related Experiment Videos

Last Updated: Jul 5, 2026

An Integrated Approach for Microprotein Identification and Sequence Analysis
09:37

An Integrated Approach for Microprotein Identification and Sequence Analysis

Published on: July 12, 2022

Investigating Protein Sequence-structure-dynamics Relationships with Bio3D-web
09:51

Investigating Protein Sequence-structure-dynamics Relationships with Bio3D-web

Published on: July 16, 2017

  • Established protocols for essential protein function prediction tasks.
  • A framework for integrating diverse prediction results was presented.
  • All necessary resources are readily available online with minimal computational expertise required.

Conclusions:

  • The proposed strategy simplifies protein function prediction using accessible web resources.
  • Biologists can effectively determine protein functions with limited computational background.
  • This approach enhances the utility of sequence analysis tools in biological research.