Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Schizophrenia01:17

Schizophrenia

Schizophrenia, a term introduced by Swiss psychiatrist Eugen Bleuler in 1911, describes a severe psychological disorder marked by profound disruptions in attention, thought processes, language, emotion, and interpersonal relationships. The core feature of schizophrenia is psychosis — a state characterized by a fundamental detachment from reality. This disconnection manifests through distorted logic, impaired perception, and atypical behavior, severely affecting the lives of those diagnosed.
Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders01:27

Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders

Schizophrenia is a neurodevelopmental disorder whose origins are rooted in complex genetic components. Despite our burgeoning understanding, the pathophysiology of this disorder remains incompletely deciphered.
Researchers have identified genetic factors that increase susceptibility to schizophrenia, underscoring the intricate interplay between genetics and environment in disease development. At the core of schizophrenia's pathophysiology is excessive dopaminergic neurotransmission within the...
Psychological and Sociocultural Causes of Schizophrenia01:29

Psychological and Sociocultural Causes of Schizophrenia

Schizophrenia, a complex psychiatric disorder, has been historically misunderstood. Early psychological theories attributed its origins to childhood trauma and unresponsive parenting. However, contemporary research largely rejects these notions, favoring the vulnerability-stress hypothesis. This model proposes that individuals with a genetic predisposition to schizophrenia may develop the disorder following exposure to significant environmental stressors. Notably, studies on high-risk...
Positive Symptoms Schizophrenia: Hallucinations and Delusions01:26

Positive Symptoms Schizophrenia: Hallucinations and Delusions

Schizophrenia is a complex psychiatric disorder characterized by a range of symptoms that significantly impact cognition, behavior, and emotional regulation. Among these, the positive symptoms stand out as they involve the addition or exaggeration of normal mental functions, deviating markedly from typical behavior and perception. Hallucinations and delusions are prominent positive symptoms, each profoundly affecting the individual's experience of reality.
Hallucinations
Hallucinations in...
Biological Causes of Schizophrenia01:29

Biological Causes of Schizophrenia

Schizophrenia, a severe psychiatric disorder, arises from a complex interplay of biological factors, including genetic predisposition, structural brain abnormalities, neurotransmitter dysregulation, and developmental irregularities. These factors collectively contribute to the onset and progression of the disorder, which typically manifests in late adolescence or early adulthood.
Genetic Factors in Schizophrenia
The genetic basis of schizophrenia is strongly supported by family and twin studies.
Positive Symptoms of Schizophrenia: Hallucinations and Delusions01:30

Positive Symptoms of Schizophrenia: Hallucinations and Delusions

Schizophrenia is a complex mental health disorder that can manifest with various positive symptoms, including thought, movement, and behavior disorders. These symptoms significantly disrupt cognitive and motor functions, leading to profound effects on an individual's ability to engage with the world.
Thought Disorders
Disorganized and unusual thought processes mark thought disorders in schizophrenia. One key feature is disorganized speech, where an individual's conversation includes loosely...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Online group exercise for people with Parkinson's disease: rehabilitation and fitness professionals' experiences to inform physiotherapy practice and service delivery - a qualitative interview study.

Physiotherapy theory and practice·2026
Same author

Impact of concurrent colonic CMV infection on clinical outcomes in immune checkpoint inhibitor-induced colitis.

European journal of cancer (Oxford, England : 1990)·2026
Same author

Bringing MOUD "In House": Implementing an Internal MOUD Program During Pregnancy in a State Prison.

Journal of correctional health care : the official journal of the National Commission on Correctional Health Care·2026
Same author

Views and Experiences of Online Exercise Groups for People With Parkinson's Disease: A Qualitative Study.

Parkinson's disease·2026
Same author

Comment on "Long-Term Outcomes Following Vaginal versus Laparoscopic Uterosacral Ligament Suspension".

International urogynecology journal·2025
Same author

Non-invasive fluorescence sensing reveals changes in intestinal barrier function and gastric emptying rate in a first-in-human study of Crohn's disease.

Therapeutic advances in gastroenterology·2025

Related Experiment Video

Updated: Jul 5, 2026

Development of a Virtual Reality Assessment of Everyday Living Skills
10:32

Development of a Virtual Reality Assessment of Everyday Living Skills

Published on: April 23, 2014

Understanding schizophrenia.

Paul Rigby1, James Alexander

  • 1School of Nursing and Midwifery, De Montfort University, Leicester. prigby@dmu.ac.uk

Nursing Standard (Royal College of Nursing (Great Britain) : 1987)
|April 24, 2008
PubMed
Summary

This article introduces schizophrenia, covering its symptoms, causes, and prognosis. It explores various therapeutic strategies for managing this complex mental health condition.

Area of Science:

  • Psychiatry
  • Neuroscience
  • Mental Health

Background:

  • Schizophrenia is a chronic, severe mental disorder.
  • It affects how a person thinks, feels, and behaves.

Purpose of the Study:

  • To provide a comprehensive overview of schizophrenia.
  • To detail its clinical presentation, etiology, and patient outcomes.
  • To review current and emerging treatment modalities.

Main Methods:

  • Literature review of existing research on schizophrenia.
  • Synthesis of information on signs, symptoms, and diagnostic criteria.
  • Analysis of etiological factors, including genetic and environmental influences.
  • Examination of prognostic indicators.
  • Overview of pharmacological and psychosocial interventions.

More Related Videos

Standardized Data Acquisition for Neuromelanin-Sensitive Magnetic Resonance Imaging of the Substantia Nigra
05:14

Standardized Data Acquisition for Neuromelanin-Sensitive Magnetic Resonance Imaging of the Substantia Nigra

Published on: September 8, 2021

Related Experiment Videos

Last Updated: Jul 5, 2026

Development of a Virtual Reality Assessment of Everyday Living Skills
10:32

Development of a Virtual Reality Assessment of Everyday Living Skills

Published on: April 23, 2014

Standardized Data Acquisition for Neuromelanin-Sensitive Magnetic Resonance Imaging of the Substantia Nigra
05:14

Standardized Data Acquisition for Neuromelanin-Sensitive Magnetic Resonance Imaging of the Substantia Nigra

Published on: September 8, 2021

Main Results:

  • Schizophrenia presents with a diverse range of positive, negative, and cognitive symptoms.
  • Etiology is multifactorial, involving genetic predisposition and environmental stressors.
  • Prognosis varies significantly among individuals.
  • Effective management often requires a combination of treatments.

Conclusions:

  • Early diagnosis and consistent treatment are crucial for improving outcomes in schizophrenia.
  • Ongoing research is vital for developing more targeted and effective therapies.
  • A multidisciplinary approach is essential for comprehensive patient care.