Related Experiment Video
Updated: Jul 5, 2026

Visualizing Scar Development Using SCAD Assay - An Ex-situ Skin Scarring Assay
Published on: April 28, 2022
Two cases of spontaneous stellate scars
Catherine van Montfrans1, Jaap Lagendijk, Donal Hayes
1Department of Dermatology, UMC Utrecht, Utrecht, The Netherlands. c.vanmontfrans@umcutrecht.nl
Abstract:
Scar formation is a physiologic reaction to dermal injury. We describe a 11-year-old girl and her 15-year-old cousin, who both presented with stellate scarlike lesions primarily located on the hands. Histopathologic examination confirmed scar tissue formation. There was no history of initiating trauma or other possible triggering factors. To our knowledge, this is the first reported case of spontaneous stellate scars in two young, second-degree family members, the exact pathogenesis of which remains to be elucidated.
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