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Sachin Agrawal1, Allan Irvine, Julian Money-Kyrle

  • 1Department of Urology, St Peters Hospital, Chertsey, UK. agrawalsachin@hotmail.com

Annals of the Royal College of Surgeons of England
|April 24, 2008
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Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
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The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...