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Related Concept Videos

Heterogeneous Catalysis01:22

Heterogeneous Catalysis

Heterogeneous catalysis involves a catalyst in a different phase from the reactants. It is a process where the catalyst and the reactants are in distinct phases, typically solid and gas or liquid.Most heterogeneous catalysts are metals, metal oxides, or acids. The list includes transition metals like iron (Fe), cobalt (Co), nickel (Ni), palladium (Pd), platinum (Pt), chromium (Cr), manganese (Mn), tungsten (W), silver (Ag), and copper (Cu). These metals possess partially vacant d orbitals that...
Introduction to Mechanisms of Enzyme Catalysis01:13

Introduction to Mechanisms of Enzyme Catalysis

For many years, scientists thought that enzyme-substrate binding took place in a simple "lock-and-key" fashion. This model stated that the enzyme and substrate fit together perfectly in one instantaneous step. However, current research supports a more refined view scientists call induced fit. The induced-fit model expands upon the lock-and-key model by describing a more dynamic interaction between enzyme and substrate. As the enzyme and substrate come together, their interaction causes a mild...
Introduction to Mechanisms of Enzyme Catalysis01:13

Introduction to Mechanisms of Enzyme Catalysis

For many years, scientists thought that enzyme-substrate binding took place in a simple "lock-and-key" fashion. This model stated that the enzyme and substrate fit together perfectly in one instantaneous step. However, current research supports a more refined view scientists call induced fit. The induced-fit model expands upon the lock-and-key model by describing a more dynamic interaction between enzyme and substrate. As the enzyme and substrate come together, their interaction causes a mild...
Catalysis02:50

Catalysis

The presence of a catalyst affects the rate of a chemical reaction. A catalyst is a substance that can increase the reaction rate without being consumed during the process. A basic comprehension of a catalysts’ role during chemical reactions can be understood from the concept of reaction mechanisms and energy diagrams.
Catalysis01:27

Catalysis

Catalysis influences the rate of chemical reactions by providing an alternative reaction pathway with lower activation energy. A catalyst speeds up a reaction, but it is not consumed during the process. The fundamental principle of catalysis is the ability of a catalyst to alter the reaction mechanism, often introducing a more efficient pathway than the uncatalyzed process.In a catalyzed reaction, the catalyst participates directly in the reaction mechanism. It interacts with reactants to form...
Enzymes02:34

Enzymes

Inside living organisms, enzymes act as catalysts for many biochemical reactions involved in cellular metabolism. The role of enzymes is to reduce the activation energies of biochemical reactions by forming complexes with its substrates. The lowering of activation energies favor an increase in the rates of biochemical reactions.
Enzyme deficiencies can often translate into life-threatening diseases. For example, a genetic abnormality resulting in the deficiency of the enzyme G6PD...

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Updated: Jul 5, 2026

Catalytic Reactions at Amine-Stabilized and Ligand-Free Platinum Nanoparticles Supported on Titania During Hydrogenation of Alkenes and Aldehydes
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Enzyme catalysis on solid surfaces.

Nicolas Laurent1, Rose Haddoub, Sabine L Flitsch

  • 1Manchester Interdisciplinary Biocentre and School of Chemistry, The University of Manchester, 131 Princess Street, Manchester M1 7DN, UK.

Trends in Biotechnology
|April 24, 2008
PubMed
Summary
This summary is machine-generated.

Enzyme-catalysed reactions using immobilised substrates on solid surfaces are vital for biotechnology. This review covers solid-phase enzyme catalysis and its applications in miniaturisation and bionanotechnology.

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In Situ SIMS and IR Spectroscopy of Well-defined Surfaces Prepared by Soft Landing of Mass-selected Ions

Published on: June 16, 2014

Area of Science:

  • Biotechnology
  • Bionanotechnology
  • Enzyme Catalysis

Background:

  • Enzyme-catalysed reactions with immobilised substrates are increasingly important in biotechnology.
  • Miniaturisation and automation in chemistry and biology drive the need for immobilised reaction components.
  • Immobilisation on surfaces like microarrays and nanoparticles addresses technical challenges in these fields.

Purpose of the Study:

  • To review enzyme-catalysed reactions performed on solid phases.
  • To discuss the applications of solid-phase enzyme catalysis in biotechnology.

Main Methods:

  • Review of literature on enzyme immobilisation techniques.
  • Analysis of enzyme-catalysed reactions on solid supports.
  • Discussion of applications in bionanotechnology and surface modification.

Main Results:

  • Enzyme catalysis offers selective and biocompatible tools for nano-scale surface modification.
  • A range of enzyme-catalysed reactions have been successfully adapted to solid-phase formats.
  • Solid-phase enzyme catalysis is applicable in various biotechnological areas.

Conclusions:

  • Solid-phase enzyme catalysis is a key technology for advancing miniaturised and automated biotechnological processes.
  • The review highlights the versatility and impact of immobilised enzymes in modern science and technology.