Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Biofilms01:29

Biofilms

Biofilms are complex communities of microorganisms encased in a self-produced extracellular polysaccharide matrix attached to surfaces. These microbial consortia can include single or multiple species, providing enhanced survival benefits by forming organized, multilayered structures.The formation of biofilms occurs through four key stages: attachment, colonization, development, and dispersal.During attachment, free-swimming planktonic cells adhere to a surface, often facilitated by...
Bacterial Signaling01:30

Bacterial Signaling

Bacterial signaling can occur within bacteria (intracellular) or between bacteria (intercellular). At times, a group of bacteria behaves like a community. To achieve this, they engage in quorum sensing, the perception of higher cell density that causes changes in gene expression. Quorum sensing involves both extracellular and intracellular signaling. The signaling cascade starts with a molecule called an autoinducer (AI). Individual bacteria produce AIs that move out of the bacterial cell...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Evaluation of clinical usefulness of a commercial multiplex PCR for diagnosing mycobacterial infections: a multicenter study.

Microbiology spectrum·2026
Same author

Ecotoxicological Risk Assessment of Anionic Surfactants, an Underestimated Pollutant: A Case Study in Mexican Lotic Waters.

Bulletin of environmental contamination and toxicology·2026
Same author

Editorial for the Special Issue "Challenges of Biofilm-Associated Bone and Joint Infections".

Microorganisms·2026
Same author

Challenges and therapeutic strategies in nontuberculous mycobacterial infections related to biofilms.

Expert review of anti-infective therapy·2026
Same author

Rifampin resistance and multidrug resistance or extensive drug resistance (MDR/XDR) predict failure in monomicrobial <i>Staphylococcus epidermidis</i> periprosthetic joint infection (PJI) - a 15-year single-center cohort study.

Journal of bone and joint infection·2026
Same author

Geographical Differences in the Epidemiology and Treatment of Candida Prosthetic Joint Infections.

Open forum infectious diseases·2026

Related Experiment Video

Updated: Jul 5, 2026

Oral Biofilm Formation on Different Materials for Dental Implants
11:19

Oral Biofilm Formation on Different Materials for Dental Implants

Published on: June 24, 2018

Bacterial adherence to SiO2-based multifunctional bioceramics.

Teemu J Kinnari1, Jaime Esteban, Enrique Gomez-Barrena

  • 1Department of Clinical Microbiology, Fundación Jiménez Díaz-UTE, Avda. de Reyes Católicos 2, ES-28040 Madrid, Spain.

Journal of Biomedical Materials Research. Part A
|April 24, 2008
PubMed
Summary

Bacterial adherence to implant materials was studied. Biphasic magnetic bioceramics showed less bacterial attachment, with MCM-41 exhibiting the lowest adherence when pore accessibility was considered.

More Related Videos

Biomimetic Materials to Characterize Bacteria-host Interactions
12:22

Biomimetic Materials to Characterize Bacteria-host Interactions

Published on: November 16, 2015

Related Experiment Videos

Last Updated: Jul 5, 2026

Oral Biofilm Formation on Different Materials for Dental Implants
11:19

Oral Biofilm Formation on Different Materials for Dental Implants

Published on: June 24, 2018

Biomimetic Materials to Characterize Bacteria-host Interactions
12:22

Biomimetic Materials to Characterize Bacteria-host Interactions

Published on: November 16, 2015

Area of Science:

  • Biomaterials Science
  • Microbiology
  • Surface Chemistry

Background:

  • Implant-related infections are a significant clinical challenge, often caused by Staphylococcus aureus and Staphylococcus epidermidis.
  • Silica-based bioceramics are investigated for orthopedic and dental applications, but their interaction with bacteria requires thorough evaluation.
  • Understanding bacterial adherence is crucial for developing infection-resistant biomaterials.

Purpose of the Study:

  • To evaluate and compare the adherence of Staphylococcus aureus and Staphylococcus epidermidis to various multifunctional silica-based bioceramics.
  • To investigate the influence of material structure, including mesoporosity and intergranular porosity, on bacterial attachment.
  • To identify bioceramic materials with reduced bacterial colonization for potential use in preventing implant-related infections.

Main Methods:

  • Four silica-based bioceramics were tested: MCM-41, SBA-15, ordered SiO2-CaO-P2O5 mesoporous glass (OMG), and biphasic magnetic bioceramic (BMB).
  • Bioceramic samples were incubated with Staphylococcus aureus and Staphylococcus epidermidis (10^8 CFU/mL) for 90 minutes.
  • Bacterial adherence was quantified after sonication to remove loosely attached bacteria, with pore accessibility analysis performed.

Main Results:

  • Biphasic magnetic bioceramic (BMB) demonstrated significantly lower adherence of both S. aureus and S. epidermidis compared to MCM-41, SBA-15, and OMG.
  • When bacterial pore accessibility was factored in, MCM-41 exhibited the lowest bacterial adherence, while SBA-15 showed the highest.
  • Higher bacterial adherence on mesoporous bioceramics was primarily attributed to intergranular porosity and grain size morphology, not the mesoporous structure itself.

Conclusions:

  • Biphasic magnetic bioceramic (BMB) shows promise for reducing bacterial colonization in implant applications.
  • Material surface characteristics, particularly intergranular porosity and grain morphology, play a critical role in bacterial adherence, potentially overriding the effect of mesoporosity.
  • Further research into optimizing bioceramic surface properties is warranted to enhance anti-infective performance.