Diabetes mellitus and non-ST elevation myocardial infarction in Thai ACS Registry

Kasem Ratanasumawong1, Smonporn Boonyaratavej, Suphot Srimahachota

  • 1Division of Cardiology, Department of Medicine, Police General Hospital, Pratumwan, Bangkok 10330, Thailand. drkasemrs@hotmail.com

Insights

Diabetic patients with non-ST elevation myocardial infarction (NSTEMI) have higher rates of congestive heart failure but not in-hospital mortality. This study highlights the high prevalence of diabetes in NSTEMI patients within the Thai ACS registry.

Area of Science:

  • Cardiology
  • Endocrinology
  • Public Health

Background:

  • Diabetes is a significant comorbidity in cardiovascular disease.
  • Understanding the impact of diabetes on non-ST elevation myocardial infarction (NSTEMI) outcomes is crucial for patient management.

Purpose of the Study:

  • To compare in-hospital morbidity and mortality between diabetic and non-diabetic patients with NSTEMI.
  • To analyze presenting characteristics and management practices in these patient groups.
  • Utilize data from the Thai ACS registry for comprehensive insights.

Main Methods:

  • Prospective, multi-center registration of 3,548 NSTEMI patients from 17 Thai hospitals over approximately 3 years.
  • Comparative analysis of demographic, clinical, and management data between diabetic and non-diabetic cohorts.
  • Statistical analysis including adjusted odds ratios to determine risk factors.

Main Results:

  • Diabetic patients (approximately 50%) exhibited higher prevalence of female sex, hypertension, and dyslipidemia.
  • Diabetic patients had an increased risk of congestive heart failure (aOR 1.84).
  • No increased risk was observed for cardiac arrhythmia, cardiac mortality, or in-hospital mortality in diabetic patients.

Conclusions:

  • A high prevalence of diabetes was noted among NSTEMI patients in the Thai ACS registry.
  • Diabetes is associated with an increased risk of congestive heart failure during hospitalization for NSTEMI.
  • Despite increased heart failure risk, diabetes did not elevate in-hospital mortality for NSTEMI patients compared to non-diabetics.
Abstract

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