Diabetes mellitus and non-ST elevation myocardial infarction in Thai ACS Registry
Kasem Ratanasumawong1, Smonporn Boonyaratavej, Suphot Srimahachota
1Division of Cardiology, Department of Medicine, Police General Hospital, Pratumwan, Bangkok 10330, Thailand. drkasemrs@hotmail.com
Insights
Diabetic patients with non-ST elevation myocardial infarction (NSTEMI) have higher rates of congestive heart failure but not in-hospital mortality. This study highlights the high prevalence of diabetes in NSTEMI patients within the Thai ACS registry.
Area of Science:
- Cardiology
- Endocrinology
- Public Health
Background:
- Diabetes is a significant comorbidity in cardiovascular disease.
- Understanding the impact of diabetes on non-ST elevation myocardial infarction (NSTEMI) outcomes is crucial for patient management.
Purpose of the Study:
- To compare in-hospital morbidity and mortality between diabetic and non-diabetic patients with NSTEMI.
- To analyze presenting characteristics and management practices in these patient groups.
- Utilize data from the Thai ACS registry for comprehensive insights.
Main Methods:
- Prospective, multi-center registration of 3,548 NSTEMI patients from 17 Thai hospitals over approximately 3 years.
- Comparative analysis of demographic, clinical, and management data between diabetic and non-diabetic cohorts.
- Statistical analysis including adjusted odds ratios to determine risk factors.
Main Results:
- Diabetic patients (approximately 50%) exhibited higher prevalence of female sex, hypertension, and dyslipidemia.
- Diabetic patients had an increased risk of congestive heart failure (aOR 1.84).
- No increased risk was observed for cardiac arrhythmia, cardiac mortality, or in-hospital mortality in diabetic patients.
Conclusions:
- A high prevalence of diabetes was noted among NSTEMI patients in the Thai ACS registry.
- Diabetes is associated with an increased risk of congestive heart failure during hospitalization for NSTEMI.
- Despite increased heart failure risk, diabetes did not elevate in-hospital mortality for NSTEMI patients compared to non-diabetics.
Objective:
To describe differences in in-hospital morbidity and mortality, presenting characteristics and management practices of diabetic and non-diabetic patients with non-ST elevation myocardial infarction using data from Thai ACS registry.
Material And Method:
Thai ACS registry is a multi-center prospective project of nationwide registration in Thailand.
Results:
The present study consisted of 3,548 patients with non-ST elevation myocardial infarction from 17 hospitals in about a 3-year period. About 50% of the patients with diabetes were more often female, with a greater prevalence of hypertension and dyslipidemia. The diabetic group was at an increased risk for congestive heart failure (adjusted odds ratio 1.84) but not increased risk for cardiac arrhythmia, cardiac mortality, and in-hospital mortality.
Conclusion:
There was a very high prevalence of diabetes in non-ST elevation myocardial infarction from ThaiACS registry. These patients were at increased risk for congestive heart failure as index of hospitalization but were not at increased risk for in-hospital mortality when compared with patients without diabetes.
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