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Updated: Jul 5, 2026

Post-Myocardial Infarction Heart Failure in Closed-chest Coronary Occlusion/Reperfusion Model in Göttingen Minipigs and Landrace Pigs
Published on: April 17, 2021
Cardiovascular late effects
1Hematology Oncology Associates of Alabama, Sylacauga, Alabama, USA.
Insights
Cancer survivors treated with cardiotoxic chemotherapy or radiation face higher risks of heart problems. Regular cardiac evaluations are crucial during follow-up to detect potential cardiovascular late effects early.
Area of Science:
- Cardiology
- Oncology
- Cancer Survivorship
Background:
- Cardiotoxic cancer therapies, including chemotherapy and mediastinal radiation, increase long-term cardiovascular risks for survivors.
- Cardiovascular late effects represent a significant concern in cancer survivorship care.
Purpose of the Study:
- To highlight the importance of cardiac monitoring in cancer survivors.
- To outline key factors for evaluating cardiac function in follow-up care.
Main Methods:
- Review of established guidelines and clinical evidence regarding cardiovascular late effects.
- Identification of risk factors, symptoms, and treatment modalities associated with cardiac complications.
Main Results:
- Cancer survivors exposed to cardiotoxic treatments are at elevated risk for cardiovascular complications.
- Cardiac evaluation should be tailored based on individual risk factors, symptoms, and treatment history.
Conclusions:
- Proactive cardiac surveillance is essential for managing cardiovascular late effects in cancer survivors.
- Early detection and management of cardiac symptoms can improve long-term outcomes for cancer survivors.
Abstract:
Cancer survivors who have received cardiotoxic chemotherapy or mediastinal radiation have an increased risk of developing cardiovascular late effects. Cardiac functioning should be evaluated during follow-up exams based on the patient's risk factors, cardiac symptoms, and type of cancer treatment received. Signs and symptoms indicative of cardiovascular late effects include dyspnea, fatigue, tachycardia, nonproductive cough, neck vein distention, coarse breath sounds, and pedal edema.
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