Related Experiment Video

Updated: Jul 5, 2026

In Vivo Infection with Leishmania amazonensis to Evaluate Parasite Virulence in Mice
06:57

In Vivo Infection with Leishmania amazonensis to Evaluate Parasite Virulence in Mice

Published on: February 20, 2020

[Three new cases of visceral leishmaniasis in Côte d'Ivoire]

S P Eholié1, A K Tanon, M Folquet-Amorissani

  • 1Service des maladies infectieuses et tropicales, BP V 3, CHU Treichville, Abidjan, Côte d'Ivoire.

Bulletin De La Societe De Pathologie Exotique (1990)
|April 25, 2008
PubMed

Insights

Visceral leishmaniasis is present in Côte d'Ivoire, affecting non-HIV patients. Further surveys are needed to identify Leishmania species, reservoirs, and vectors for better control.

Area of Science:

  • Infectious Diseases
  • Tropical Medicine
  • Parasitology

Background:

  • Visceral leishmaniasis (VL) is a serious parasitic disease.
  • VL is endemic in many tropical and subtropical regions.
  • Data on VL in Côte d'Ivoire is limited.

Observation:

  • Three cases of VL in non-HIV infected native patients in Côte d'Ivoire are reported.
  • Cases included adults and a child with associated conditions like leukemia and lymphoma.
  • Clinical presentation involved fever, wasting, and pancytopenia.

Findings:

  • Diagnosis confirmed by Leishmania detection in bone marrow, lymph nodes, and spleen.
  • Treatment with amphotericin B and Glucantim was unsuccessful.
  • Leishmania species were not identified.

Implications:

  • These cases highlight VL as a significant health issue in Côte d'Ivoire.
  • An epidemiological survey is crucial to identify Leishmania species, reservoirs, and vectors.
  • Understanding transmission dynamics is vital for disease control and prevention.

More Related Videos

Intravital Microscopy Imaging of the Liver following Leishmania Infection: An Assessment of Hepatic Hemodynamics10:48

Intravital Microscopy Imaging of the Liver following Leishmania Infection: An Assessment of Hepatic Hemodynamics

Published on: July 28, 2015

In vivo Imaging of Transgenic Leishmania Parasites in a Live Host09:53

In vivo Imaging of Transgenic Leishmania Parasites in a Live Host

Published on: July 27, 2010

Related Concept Videos

Leishmaniasis01:30

Leishmaniasis

Leishmaniasis is a protozoal disease caused by species of the genus Leishmania and transmitted through the bite of infected female sandflies. The parasite exists in two principal morphological forms during its life cycle. A sandfly acquires intracellular amastigotes from an infected reservoir host, such as a dog. Within the sandfly, these forms differentiate into motile, flagellated promastigotes. During a subsequent blood meal, promastigotes are injected into the human host, where they...
American Trypanosomiasis01:22

American Trypanosomiasis

Chagas disease, or American trypanosomiasis, is a vector-borne parasitic infection caused by Trypanosoma cruzi, a flagellated protozoan (kinetoplastid) of the family Trypanosomatidae. The disease is endemic in Latin America, although cases are increasingly reported worldwide due to human migration. Transmission most commonly occurs when feces of infected triatomine bugs contaminate bite wounds or mucosal surfaces; additional routes include congenital, transfusional, transplant-related, and oral...
Antiprotozoal Agents01:21

Antiprotozoal Agents

Leishmaniasis is a widespread parasitic disease caused by several Leishmania species. It affects millions of people each year and remains a major public health problem in endemic regions. First-line treatment relies on pentavalent antimonials, including meglumine antimoniate and sodium stibogluconate. Even so, how these drugs work has not been fully clear, especially their interaction with parasite-specific biochemical pathways. One key target is trypanothione reductase (TR), an enzyme that...
Infectious Diseases and Their Occurrence01:28

Infectious Diseases and Their Occurrence

Infectious diseases appear in populations through various transmission patterns, influenced by pathogen characteristics, population immunity, environmental conditions, and social behavior. Understanding these patterns is essential for effective public health surveillance and intervention. These categories—sporadic, outbreak, epidemic, pandemic, and endemic—help frame the nature and scope of disease events.Sporadic diseases occur irregularly and infrequently, without a predictable temporal or...
Malaria01:29

Malaria

Malaria pathogenesis in humans reflects a delicate interplay between parasite biology and host response. Clinical illness reflects a host’s immune response to the parasite’s asexual replication cycle, which is often asymptomatic in individuals with partial immunity. From the parasite's perspective, transmission between mosquito and human with minimal host pathology is evolutionarily advantageous. Among the six Plasmodium species infecting humans, P. falciparum and P. vivax dominate in global...
Giardiasis01:12

Giardiasis

Giardiasis is a globally prevalent intestinal infection caused by the protozoan parasite Giardia duodenalis (also known as G. lamblia or G. intestinalis). This flagellated protozoan is the most frequently identified intestinal parasite in the United States and worldwide. Transmission primarily occurs via the fecal-oral route, with infection arising from ingestion of water or food contaminated with cysts. Individuals in low-resource settings, international travelers, outdoor enthusiasts, daycare...