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Updated: Jul 5, 2026

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A Preclinical Mouse Model of Osteosarcoma to Define the Extracellular Vesicle-mediated Communication Between Tumor and Mesenchymal Stem Cells
Published on: May 6, 2018
Mouse SaI sarcoma tumor model
1University of Maryland Baltimore County, Baltimore, Maryland, USA.
Current Protocols in Immunology
|April 25, 2008
Abstract:
SaI is an A/J-derived (H-2K(k)D(d)) transplantable mouse fibrosarcoma that produces a solid tumor when inoculated subcutaneously, intradermally, or intramuscularly, and an ascites tumor when inoculated intraperitoneally into syngeneic mice. This unit describes the establishment of primary solid SaI/N tumor, the establishment of SaI ascites tumor, and the removal for sampling of in vivo-passaged SaI ascites tumor cells in mice.
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