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Updated: Jul 5, 2026

Establishment of Deep Hypothermic Circulatory Arrest in Rats
Published on: December 16, 2022
Massive pulmonary embolism with cardiac arrest treated with continuous thrombolysis and concomitant hypothermia
A Hovland1, H Bjørnstad, R F Hallstensen
1Coronary Care Unit, Medical Department, Nordland Hospital, 8092 Bodo, Norway. a-hovlan@online.no
Abstract:
This case report describes the clinical course in a 49-year-old man with repeated cardiac arrests due to massive pulmonary embolism. He was successfully treated with intravenous tenecteplase followed by catheter-based alteplase infusion during external cooling. The case illustrates that vitally important bolus thrombolytic therapy may be continued as catheter-based treatment along with hypothermia without significant bleeding complications.
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Assessment:
1. Clinical Evaluation:
History:
