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Transitioning health care responsibility from caregivers to patient: a pilot study aiming to facilitate medication
Rachel A Annunziato1, Sukru Emre, Benjamin L Shneider
1Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA. rachel.annunziato@mssm.edu
Insights
A pilot study shows that educating pediatric transplant patients on managing their own health is feasible. This intervention improved medication adherence and liver function in adolescents transitioning to adult care.
Area of Science:
- Pediatric Transplant Care
- Adolescent Health Transition
- Medical Education
Background:
- Pediatric transplant recipients undergo a critical transition involving shifts in medical care and responsibility.
- Facilitating the transfer of health care responsibilities from caregivers to patients is essential for long-term outcomes.
Purpose of the Study:
- To assess the feasibility of a pilot educational intervention for pediatric transplant patients.
- To aid in the transition of health care responsibilities from caregivers to patients within the pediatric setting.
Main Methods:
- A two-session educational protocol was implemented in an outpatient transplant clinic.
- Twenty-two pediatric transplant recipients were enrolled, with data analyzed for 20 patients.
- Medical outcomes included medication adherence (tacrolimus levels) and alanine aminotransferase (ALT) levels.
Main Results:
- Mean ALT levels significantly improved post-intervention (p < 0.01).
- Tacrolimus blood level variability decreased, indicating improved medication adherence (p = 0.04).
- Maximal ALT values also showed a significant overall decrease (p = 0.03).
Conclusions:
- Targeted education for adolescents in managing their own health is feasible in outpatient pediatric transplant settings.
- This approach may support families during the challenging health care transition process.
- Further randomized controlled trials are needed to confirm efficacy.
Abstract:
Transition in pediatric transplant recipients consists of both a physical shift in medical care location as well as a transition in health care responsibilities from caregivers to patients. The purpose of the present study was to test the feasibility of a pilot intervention aiming to facilitate the transition in health care responsibilities from caregivers to patients while patients are still receiving pediatric services. Twenty-two patients were enrolled in a two-session educational protocol aiming to facilitate transition of responsibility. Patients were recruited from an outpatient transplant clinic. Ten were referred because of suspected difficulty in transitioning of care, and 12 were consecutively recruited without any specific a priori concerns. Medication adherence, measured through the use of standard deviations of tacrolimus blood levels, and ALT levels were the medical outcome measures. Complete data are available for 20 patients. Mean ALT levels improved after the follow-up period. For referred patients, adherence and ALT levels improved. Standard deviation of tacrolimus decreased from 3.33 to 2.23, t = 2.52, p = 0.04. Mean ALT decreased from 120.33 to 63.99, t = 3.01, p = 0.01. Maximal ALT values decreased overall from 284.10 to 101.20, t = 2.61, p = 0.03. Our findings suggest that targeted education regarding transition in responsibility for adolescents' own health care is feasible in the outpatient environment and may assist families who are facing this potentially challenging process. A randomized, controlled study with a substantial number of enrolled patients is needed to establish the efficacy of this or other approaches.
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