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Feline primary open angle glaucoma.

Susan Jacobi1, Richard R Dubielzig

  • 1Department of Small Animal Clinical Sciences, Veterinary Teaching Hospital, Michigan State University, East Lansing, MI, USA.

Veterinary Ophthalmology
|April 26, 2008
PubMed
Summary
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Primary open angle glaucoma in cats is a rare condition. This study details the histomorphological features of eight feline cases, noting optic nerve damage and other changes.

Area of Science:

  • Veterinary Ophthalmology
  • Ophthalmic Pathology

Background:

  • Feline glaucoma is a significant concern in veterinary medicine.
  • Primary open angle glaucoma (POAG) is a specific subtype requiring detailed characterization.

Purpose of the Study:

  • To document the histomorphological features of feline primary open angle glaucoma.
  • To contribute to the understanding of this rare feline ocular disease.

Main Methods:

  • Retrospective study of eight feline eyes diagnosed with POAG.
  • Histopathological examination of globe sections using H&E and alcian blue stains.
  • Exclusion of cases not meeting POAG criteria.

Main Results:

  • Significant findings included open irido-corneal angles and ciliary clefts.

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  • All cases showed loss of ganglion cells.
  • Optic nerve head cupping and gliosis were observed in sampled nerves.
  • Myxomatous stromal changes near vortex veins were noted in most cases.

    • Conclusions:

    • Feline POAG is rare but important to consider in glaucoma investigations.
    • The pathogenesis of aqueous outflow obstruction in these cases remains unknown.
    • This study adds eight new cases of idiopathic feline POAG to the literature.