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Related Experiment Video

Updated: Jul 5, 2026

Real-Time Void Spot Assay

Real-Time Void Spot Assay

Published on: February 10, 2023

Predictors of delayed first voiding in newborn.

Tuomo Vuohelainen¹, Riitta Ojala, Anita Virtanen

¹Paediatric Research Centre, University of Tampere and Tampere University Hospital, Department of Pediatrics, Tampere, Finland.

Acta Paediatrica (Oslo, Norway : 1992)

|April 26, 2008

Summary

Delayed first voiding in newborns is linked to prolonged, stressful births. This may indicate increased arginine vasopressin (AVP) and aldosterone secretion, impacting infant kidney function.

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How to Obtain Reliable Visual Event-related Potentials in Newborns

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How to Obtain Reliable Visual Event-related Potentials in Newborns

How to Obtain Reliable Visual Event-related Potentials in Newborns

Published on: October 24, 2019

Area of Science:

Neonatal Physiology
Pediatric Nephrology
Reproductive Medicine

Background:

Delayed first voiding (>24 hours) in neonates, while often benign, warrants investigation.
Maternal stress during birth can elevate fetal arginine vasopressin (AVP) and aldosterone levels.

Purpose of the Study:

To identify predictors of delayed first voiding in newborns.
To find indirect evidence of AVP's role in delayed neonatal voiding.

Main Methods:

Compared 20 newborns with delayed voiding (>24h) to 19 controls (<24h).
Analyzed first urine for osmolality (U-Osm) and sodium content (U-Na).
Assessed maternal and birth factors, including parity, labor duration, and cardiotocography (CTG).

Main Results:

Higher U-Osm and lower U-Na in neonates with delayed voiding.
Delayed voiding associated with primiparous mothers, longer labor (both stages), and abnormal CTGs.
All abnormal CTGs occurred in the delayed voiding group.

Conclusions:

Delayed neonatal voiding is associated with prolonged and stressful birth experiences.
Elevated urine osmolality and sodium levels suggest increased AVP and aldosterone secretion in these infants.