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Published on: October 2, 2014
[Epilepsy surgery during infancy and early childhood in France]
C Bulteau1, G Dorfmüller, M Fohlen
1Service de neurochirurgie pédiatrique, fondation ophtalmologique Adolphe-de-Rothschild, 25-29, rue Manin, 75940 Paris cedex 19, France. cbulteau@fo-rothschild.fr
Insights
Epilepsy surgery in children is active in France, with 80-100 procedures annually for drug-resistant epilepsy. Most patients are under 10, highlighting the need for specialized pediatric epilepsy surgery centers.
Area of Science:
- Pediatric Neurology
- Neurosurgery
- Epileptology
Background:
- The Fondation Rothschild Hospital is France's primary center for pediatric epilepsy surgery.
- This study details the center's surgical activity for epilepsy in infants and children.
Purpose of the Study:
- To present the epilepsy surgery activity in infants and children.
- To analyze patient demographics, evaluation methods, and surgical procedures.
Main Methods:
- Prospective study from 2003-2007.
- Involved three patient groups: surgical candidates, those undergoing presurgical evaluation, and those having surgery.
- Utilized EEG, foramen ovale electrodes, and invasive recording techniques.
Main Results:
- 304 children were evaluated as surgical candidates; 61% were included in the program.
- 296 children underwent presurgical evaluation, with 70% under 10 years old.
- 316 children had surgery, including focal resection, hemispherotomy, hypothalamic hamartoma resection, and palliative procedures.
Conclusions:
- 80-100 children undergo epilepsy surgery annually at the center.
- Approximately 70% of surgically treated children are under 10 years of age.
- This activity is integrated within a network of pediatric neurologists managing severe childhood epilepsy.
Background And Purpose:
We present the epilepsy surgery activity in infants and children at the Fondation Rothschild Hospital, the main center dedicated to this activity in France.
Method:
A prospective study was conducted from 2003 to 2007 based on three populations: (1) children selected as candidates for surgery, (2) children undergoing presurgical evaluation and (3) children undergoing surgical procedures for epilepsy.
Results:
Children selected as candidates for surgery: 304 children were referred and discussed by our multidisciplinary staff. They came from Paris and its suburbs (40%), the provinces (43%) or from other countries (14%). Sixty-one percent of them were included in our surgery program and 24% were excluded. Sixty-one percent of them were under 10 years of age. Children undergoing presurgical evaluation: 296 children were recorded: 140 EEG (47%), 46 with foramen ovale electrodes (16%) and 110 with invasive recording techniques (37%). Seventy percent of these children were under 10 years of age. Children undergoing surgical procedures: 316 children underwent surgery; 68% of them were under 10 years of age. The surgical procedures were focal resection (136 children), vertical parasagittal hemispherotomy (77 children), resection and or disconnection for hypothalamic hamartoma (69 children) and 34 had palliative surgery (callosotomy or vagal nerve stimulation).
Conclusion:
Eighty to 100 children undergo surgery each year in our department for drug-resistant partial epilepsy; 70% of them are less than 10 years of age. This activity is part of a network of pediatric neurologists who are deeply involved in treatment of severe epilepsy in children.
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