Diagnostic value of serum lipoprotein X in jaundice

The presence of lipoprotein X (LPX) was assessed in the serum of 61 jaundiced patients and of 41 patients without liver disease. The results are compatible with the reports of other authors that the presence of LPX is a more sensitive indicator of cholestasis than the serum alkaline phosphatase (SAP) level. However, the latter was more useful in excluding the presence of extrahepatic obstruction.