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Published on: January 29, 2018
Bone mineral density and correlation factor analysis in normal Taiwanese children
1Department of Pediatrics, Taichung Veterans General Hospital, Taiwan. ssgs@vghtc.gov.tw
Acta Paediatrica Taiwanica = Taiwan Er Ke Yi Xue Hui Za Zhi
|April 29, 2008
Summary
This study provides reference data for lumbar bone mineral density (BMD) in healthy Taiwanese children aged 4-18. Linear regression equations were developed, highlighting the influence of bone age and puberty on BMD.
Area of Science:
- Pediatric Endocrinology
- Bone Health Research
- Anthropometry
Background:
- Establishing normative data for lumbar bone mineral density (BMD) is crucial for pediatric health assessment.
- Investigating factors influencing BMD in children is essential for understanding growth and development.
Purpose of the Study:
- To establish reference data and linear regression equations for lumbar BMD in normal Taiwanese children.
- To identify key factors influencing lumbar BMD in a pediatric population.
Main Methods:
- Recruited 257 healthy children (136 boys, 121 girls) aged 4-18 years.
- Measured height, weight, blood pressure, puberty stage, bone age, and lumbar BMD (L2-4) using dual-energy x-ray absorptiometry (DEXA).
- Analyzed data using Pearson correlation and stepwise regression.
Main Results:
- Lumbar BMD and related parameters increased with age in both genders.
- Bone age and puberty stage showed significant influence on BMD, comparable to or exceeding that of height and weight.
- Multiple linear regression equations were formulated for boys and girls.
Conclusions:
- The generated BMD reference data can aid in monitoring childhood pathological conditions.
- Adjustments to BMD interpretation may be necessary for children with abnormal bone age or pubertal development.
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