[The long-term contrastive result of neo-urethra reconstructed with different kinds of tissue]
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Updated: Jul 5, 2026

Surgical Model for Single-Staged Tissue-Engineered Urothelial Tubes in Minipigs
Published on: July 5, 2024
Ju-Feng Fan1, Sen-Kai Li, Yang-Qun Li
1Plastic Surgery Hospital of CAMS, Beijing, China.
Objective:
To observe the long-term apparent and structural change of the neo-urethra inner wall reconstructed with different kinds of tissue. To compare the difference between normal and reconstructed urethra for urethra reconstruction with more appropriate materials.
Methods:
The neo-urethra inner wall was observed during operation, through urography and urethroscope. The tissue section of neo-urethra inner wall was observed through light microscope and electron microscope.
Results:
With unchanged structure, the appearance of neo-urethra reconstructed with skin or mucosa could be close to normal urethra after a long time. Neo-urethra made of buccal mucosa possesses some of the most important basic structures for normal urethral microenvironment to form. The structure of neo-urethra made of bladder could be close to normal urethra after a long time.
Conclusions:
Buccal and bladder mucosa may be a better material than skin for urethra reconstruction.
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