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Related Experiment Video

Updated: Jul 5, 2026

Electrophysiological Analysis of human Pluripotent Stem Cell-derived Cardiomyocytes (hPSC-CMs) Using Multi-electrode Arrays (MEAs)
11:13

Electrophysiological Analysis of human Pluripotent Stem Cell-derived Cardiomyocytes (hPSC-CMs) Using Multi-electrode Arrays (MEAs)

Published on: May 12, 2017

[Programmable multichannel electrophysiological stimulator based on MCU and CPLD platform].

Yi Zheng1, Xiao-Mei Wu, Zu-Xiang Fang

  • 1Dept. of Electronic Engineering, Fudan University, Shanghai 200433.

Zhongguo Yi Liao Qi Xie Za Zhi = Chinese Journal of Medical Instrumentation
|April 29, 2008
PubMed
Summary

This study introduces a programmable multichannel stimulator for precise electrical stimulation. It utilizes optical coupling and a float ground for enhanced safety in physiological measurements.

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Area of Science:

  • Neuroscience
  • Biomedical Engineering
  • Electrical Engineering

Context:

  • Developing advanced tools for precise neural stimulation is crucial for understanding brain function and developing new therapies.
  • Existing stimulation systems often face challenges with safety, isolation, and precise control over stimulation parameters.

Purpose:

  • To design and implement a programmable multichannel stimulator for controlled electrical stimulation of neural tissues.
  • To achieve high safety standards for physiological measurements by employing novel isolation techniques.

Summary:

  • A programmable multichannel stimulator was developed, controlled by a microcontroller unit (MCU) and a complex programmable logic device (CPLD).
  • The stimulator delivers electrical stimuli with adjustable amplitude and width to an electrode array in various modes.

Related Experiment Videos

Last Updated: Jul 5, 2026

Electrophysiological Analysis of human Pluripotent Stem Cell-derived Cardiomyocytes (hPSC-CMs) Using Multi-electrode Arrays (MEAs)
11:13

Electrophysiological Analysis of human Pluripotent Stem Cell-derived Cardiomyocytes (hPSC-CMs) Using Multi-electrode Arrays (MEAs)

Published on: May 12, 2017

  • Optical coupling and a stable float ground connection replace traditional transformer isolation, ensuring safety for physiological measurements.

    • Impact:

    • This device offers a safer and more precise platform for electrophysiological research and potential therapeutic applications.
    • The novel safety features enhance the reliability and applicability of multichannel stimulation in biological research settings.