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Updated: Jul 5, 2026

Three-Dimensional Cell Culture Models to Investigate the Epithelial Barrier in Eosinophilic Esophagitis
Published on: May 10, 2024
[Eosinophilic fasciitis; the importance of early detection for optimal outcomes]
J W E Hokken1, A W L van den Wall Bake, R N J de Nijs
1Afd. Interne Geneeskunde, Máxima Medisch Centrum, Veldhoven. esmeraldahokken@hotmail.com
Abstract:
Eosinophilic fasciitis (EF) is a disease with unknown aetiology, although an immunologic pathogenesis is suspected. The characteristic features of this inflammatory disease include scleroderma-like skin indurations, predominantly on the extremities, and peripheral blood eosinophilia. Internal organs are generally not affected. Initiation of systemic glucocorticoid therapy at an early stage results in a good response and remission of symptoms. This is illustrated in 3 cases of EF to demonstrate the importance of early detection in this disease.
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