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Updated: Jul 5, 2026

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Bone response to a Ca- and P-enriched titanium surface obtained by anodization.

Rosemeire de Lordo Franco1, Roberto Chiesa, Paulo Tambasco de Oliveira

  • 1Cell Culture Laboratory, School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil.

Brazilian Dental Journal
|April 29, 2008
PubMed
Summary

This study shows a multiphase anodic spark deposition coating (BSP-AK) on titanium implants may enhance bone formation. While not statistically significant, the BSP-AK surface demonstrated a trend towards improved bone-to-implant contact.

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Area of Science:

  • Biomaterials Science
  • Orthopedic Research
  • Surface Engineering

Background:

  • Titanium (Ti) implants are widely used in orthopedics.
  • Enhancing bone integration with implant surfaces is crucial for successful osseointegration.
  • Surface modifications aim to improve the biological response of metallic implants.

Purpose of the Study:

  • To evaluate the bone response to a calcium- and phosphorus-enriched titanium surface.
  • To assess the effect of a multiphase anodic spark deposition coating (BSP-AK) on bone-to-implant contact.
  • To compare the osseointegration potential of BSP-AK treated Ti implants versus machined Ti controls.

Main Methods:

  • Bilateral implantation of BSP-AK treated and untreated (machined) Ti cylinders in canine humerus.

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Last Updated: Jul 5, 2026

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  • Histologic and histomorphometric analyses of bone fragments at 8 weeks postimplantation.
  • Evaluation of bone formation, collagen fiber orientation, and bone-to-implant contact percentages.
  • Main Results:

    • Bone formation was observed in both cortical and medullary areas around implants.
    • Collagen fiber bundles were oriented parallel to Ti surfaces in the medullary area.
    • Mean bone-to-implant contact was 2.3% for BSP-AK and 0.4% for control, indicating a trend favoring the treated surface.

    Conclusions:

    • The BSP-AK surface shows a trend towards supporting contact osteogenesis.
    • This surface modification may enhance bone response in an experimental model with low bone-to-implant contact.
    • Further studies are warranted to confirm the efficacy of BSP-AK for improved osseointegration.