Related Experiment Video
Updated: Jul 5, 2026
10:19
A Murine Model of Group B Streptococcus Vaginal Colonization
Published on: November 16, 2016
Bacteremia caused by group G Streptococci, taiwan
Chun-Hsing Liao1, Liang-Chun Liu, Yu-Tsung Huang
1Far-Eastern Memorial Hospital, Taipei, Taiwan.
Emerging Infectious Diseases
|April 29, 2008
Summary
Group G streptococcal bacteremia, primarily caused by Streptococcus dysgalactiae subspecies equisimilis, commonly presented as cellulitis. This study found a low mortality rate but high resistance to quinupristin-dalfopristin.
Area of Science:
- Infectious Diseases
- Microbiology
- Epidemiology
Background:
- Group G Streptococcus (GGS) is an important cause of human infections.
- Streptococcus dysgalactiae subspecies equisimilis (SDSE) is the predominant GGS species.
- Understanding the clinical characteristics and outcomes of GGS bacteremia is crucial for patient management.
Purpose of the Study:
- To describe the clinical features, management, and outcomes of patients with GGS bacteremia.
- To identify risk factors for recurrence and mortality.
- To assess antimicrobial resistance patterns.
Main Methods:
- Retrospective observational study conducted in Taiwan from 1998 to 2004.
- Inclusion of 92 patients diagnosed with GGS bacteremia.
- Data collection on patient demographics, clinical diagnoses, treatment, and outcomes.
Main Results:
- SDSE accounted for 86 of 92 GGS bacteremia cases.
- Cellulitis was the most common diagnosis (48 cases), followed by primary bacteremia (34 cases).
- Recurrence was observed in 9 patients, with a low overall mortality rate of 3.3%.
- High resistance rates to quinupristin-dalfopristin were noted.
Conclusions:
- SDSE is the primary cause of GGS bacteremia in this Taiwanese cohort.
- Cellulitis and primary bacteremia are the most frequent presentations.
- While mortality is low, antimicrobial resistance, particularly to quinupristin-dalfopristin, is a significant concern.
Related Concept Videos
01:18Bacterial Gastroenteritis
Bacterial gastroenteritis, characterized by diarrhea, abdominal cramps, and vomiting, is often caused by ingestion of contaminated food or water and is frequently associated with pathogenic Escherichia coli strains. These microbes exploit two principal mechanisms to inflict disease.Shiga toxin–producing E. coli, also referred to as STEC—notably O157:H7—release Shiga toxins that target ribosomes, blocking protein synthesis. The B subunit of the toxin binds the host glycolipid receptor...
01:27Streptococcal Pharyngitis
Streptococcal pharyngitis, commonly known as “strep throat,” is an acute infection of the oropharyngeal tissues caused by the Gram‑positive Group A Streptococcus (Streptococcus pyogenes). Transmission occurs primarily through respiratory droplets expelled during coughing, sneezing, or talking.Mechanisms of Host Entry and Immune EvasionUpon entering the host, S. pyogenes adheres to the mucosal epithelial cells of the pharynx via surface proteins, notably lipoteichoic acid and the antiphagocytic...
01:22Bacterial Meningitis I: Introduction
Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...
01:24Bacterial Meningitis
Bacterial meningitis is a severe infectious disease involving inflammation of the meninges, the protective membranes surrounding the brain and spinal cord. It occurs when pathogenic bacteria cross the blood–brain barrier and enter the cerebrospinal fluid. Common causative organisms include Neisseria meningitidis, Streptococcus pneumoniae, Haemophilus influenzae type b, Listeria monocytogenes, and Escherichia coli K1. The exact route of entry varies by pathogen and host condition.Routes of Entry...
01:14Atypical Pneumonia
Atypical pneumonia, often caused by Mycoplasma pneumoniae, is a form of pulmonary infection that differs from the classical presentation of bacterial pneumonia in both its cause and clinical symptoms. Mycoplasma pneumoniae is a pleomorphic bacterium notable for its lack of a rigid cell wall. This structural characteristic imparts resistance to beta-lactam antibiotics and significantly influences the bacterium’s behavior within the human host.Other pathogens responsible for the disease include...
01:26Bacterial Meningitis II: Pathophysiology
Bacterial meningitis typically begins when pathogens such as Neisseria meningitidis and Streptococcus pneumoniae colonize the nasopharynx and invade the bloodstream. This process is facilitated by bacterial virulence factors, such as polysaccharide capsules, which resist phagocytosis and complement-mediated killing. Less commonly, bacteria reach the central nervous system via contiguous spread from infections like otitis media or sinusitis, through congenital or acquired dural defects, or...