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Electromagnetic Source Imaging in Presurgical Evaluation of Children with Drug-Resistant Epilepsy
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Multiple reversible MRI abnormalities associated with SESA syndrome.

Jean-Marc Bugnicourt1, Bruno Bonnaire, Candice Picard

  • 1Department of Neurology, Amiens University Hospital, and INSERM, ERI12, University of Picardie, Amiens, France. bugnicourt.jean-marc@chu-amiens.fr

Seizure
|April 29, 2008
PubMed
Summary

Subacute encephalopathy with seizures in alcoholics (SESA) syndrome can cause reversible brain changes on MRI, mimicking status epilepticus. This case highlights unique imaging findings in alcoholic encephalopathy.

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Area of Science:

  • Neurology
  • Radiology
  • Neuroimaging

Background:

  • Alcoholism is a significant public health issue associated with various neurological complications.
  • Subacute encephalopathy with seizures in alcoholics (SESA) syndrome is a rare but serious condition.
  • Understanding the neuroimaging features of SESA syndrome is crucial for accurate diagnosis and management.

Observation:

  • A patient with a history of alcoholism presented with delirium and recurrent left hemiparesis.
  • Clinical presentation met the diagnostic criteria for subacute encephalopathy with seizures in alcoholics (SESA) syndrome.
  • Magnetic Resonance Imaging (MRI) was performed to evaluate the neurological deficits.

Findings:

  • MRI revealed widespread, reversible signal abnormalities in the right cerebral hemisphere.

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  • These signal changes were evident on T2-weighted and diffusion-weighted imaging (DWI).
  • Apparent diffusion coefficient (ADC) values were decreased in the affected areas, indicating restricted diffusion.

    • Implications:

    • The imaging characteristics of SESA syndrome on MRI appear similar to those observed in status epilepticus.
    • This finding suggests potential overlap in the underlying pathophysiology or imaging manifestations.
    • Further research is warranted to elucidate the precise relationship between SESA syndrome and status epilepticus on neuroimaging.