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Related Experiment Video

Updated: Jul 5, 2026

$Subcutaneous Trigeminal Nerve Field Stimulation for Refractory Facial Pain$

Subcutaneous Trigeminal Nerve Field Stimulation for Refractory Facial Pain

Published on: May 10, 2017

[Familial trigeminal neuralgia].

H El Otmani¹, F Moutaouakil, H Fadel

¹Service de neurologie, hôpital Al Kortobi, B.P. 90000, Tanger, Morocco. hichamotmani@hotmail.com

Revue Neurologique

|April 29, 2008

Summary

Familial trigeminal neuralgia, a rare condition, often follows an autosomal dominant inheritance pattern. This case highlights a family cluster, suggesting a genetic basis for the disorder.

Area of Science:

Neurology
Genetics

Background:

Trigeminal neuralgia (TN) is typically sporadic, affecting individuals without a family history.
Familial cases of TN are infrequently reported in medical literature.

Observation:

A 45-year-old man presented with V2 trigeminal neuralgia, unresponsive to initial etiological investigations.
Carbamazepine provided significant symptom relief.
A review revealed TN clustering in four other family members across three generations.

Findings:

The presented case and literature review suggest an autosomal dominant inheritance pattern for familial trigeminal neuralgia.
This pattern indicates a strong genetic predisposition in affected families.

Implications:

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Understanding the genetic basis of familial TN can inform diagnostic approaches and genetic counseling.

Further research into the pathophysiology of genetically linked TN is warranted.