Molecular phylogenetic analysis of Candida tropicalis isolates by multi-locus sequence typing
Mette D Jacobsen1, Amanda D Davidson, Shu-Ying Li
1Aberdeen Fungal Group, Institute of Medical Sciences, Aberdeen AB25 2ZD, UK.
Abstract:
Multi-locus sequencing data for 242 different isolates of Candida tropicalis generated a dendrogram showing 235 strains assigned to a single large recently evolved group which contained several small clonal clusters. Haplotype analysis of a representative strain subset revealed a high level of recombination events in an otherwise clonal population. Pairs of isolates from single sources showed non-identity attributable to loss of heterozygosity in some genes in a manner similar to that established for C. albicans.
Related Concept Videos
Modern Molecular Taxonomy
Applications of Molecular Taxonomy
Evolutionary Relationships through Genome Comparisons
Microbial Phylogeny
Methods of Classification and Identification

