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Updated: Feb 11, 2026

Evaluation of Capillary and Other Vessel Contribution to Macular Perfusion Density Measured with Optical Coherence Tomography Angiography
Published on: February 18, 2022
Optical coherence tomography predictive factors for macular hole surgery outcome
J M Ruiz-Moreno1, C Staicu, D P Piñero
1Albacete Medical School, University of Castilla La Mancha, Albacete, Spain.
Preoperative optical coherence tomography (OCT) measurements can predict successful macular hole (MH) surgery outcomes. A smaller minimum diameter or higher Tractional Hole Index (THI) indicates a good visual prognosis after MH surgery.
Area of Science:
- Ophthalmology
- Retinal Surgery
- Diagnostic Imaging
Background:
- Macular hole (MH) surgery aims to restore visual acuity.
- Predicting surgical outcomes is crucial for patient management.
- Optical coherence tomography (OCT) provides detailed macular imaging.
Purpose of the Study:
- To assess the predictive value of preoperative OCT findings for MH surgery success.
- To identify specific OCT parameters that correlate with visual prognosis.
- To establish cut-off values for predictive OCT measurements.
Main Methods:
- Retrospective analysis of 46 eyes undergoing pars plana vitrectomy for MH.
- Preoperative and postoperative OCT measurements included MH minimum diameter, base diameter, height, MHI, DHI, and THI.
- Receiver operating characteristic (ROC) curve analysis was used to determine predictive factors.
Main Results:
- MH minimum diameter (p<0.01), base diameter (p=0.01), THI (p=0.04), and MHI (p=0.03) significantly correlated with visual acuity at 3 months post-surgery.
- Diameter Hole Index (DHI) and MH height did not show significant correlation.
- ROC analysis yielded cut-off values of <311 microm for minimum diameter and >1.41 for THI.
Conclusions:
- Preoperative MH minimum diameter <311 microm is a predictor of good visual outcome.
- A preoperative THI >1.41 is also a significant predictor of favorable visual prognosis after MH surgery.
- OCT parameters offer valuable insights for predicting MH surgery success.
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