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Updated: Jul 5, 2026

Spontaneous Murine Model of Anaplastic Thyroid Cancer
Published on: February 3, 2023
Chronic bronchitis mimicking metastases from thyroid medullary carcinoma demonstrated by indium-111 pentetreotide
Savas Karyagar1, Mehmet Mulazimoglu, Sevda S Karyagar
1Department of Nuclear Medicine, Okmeydani Training and Research Hospital, Istanbul, Turkey. skaryagar@yahoo.com
Abstract:
We present a case of medullary thyroid carcinoma (MTC) with pulmonary symptoms, elevated calcitonin and CEA levels. Both [111In]pentetreotide (Octreoscan) scintigraphy and 2-deoxy-2-[18F]fluoro-D-glucose positron emission tomography/computed tomography (FDG-PET/CT) scan revealed mild increased uptake of radionuclides in the upper lobe of the right lung compatible with metastases. Histopathological analysis showed it to be chronic bronchitis. The patient was followed without any treatment. Three months later, no pathological uptake on [111In]pentetreotide (Octreoscan) was observed. False positive [111In]pentetreotide uptake in the lungs was likely related to acute exacervation of the chronic bronchitis.
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