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Related Concept Videos

Menopause01:28

Menopause

Menopause, a natural biological process marking the end of a woman's fertility, typically occurs between the fifth and sixth decade of life. This phase is characterized by the exhaustion of the ovarian follicle pool, leading to less responsive ovaries despite the high levels of Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH). The consequential decrease in estrogen production results in symptoms like hot flashes, heavy sweating, headaches, hair loss, muscle pains, vaginal...
Disorders of the Female Reproductive System01:24

Disorders of the Female Reproductive System

The female reproductive system can be affected by several disorders, including Premenstrual Syndrome (PMS), Premenstrual Dysphoric Disorder (PMDD), endometriosis, and various forms of cancer. PMS and PMDD are cyclical conditions that cause physical and emotional distress, with symptoms that include edema, mood swings, and food cravings. PMDD is a more severe form of PMS characterized by increased symptom severity that peaks during the luteal phase and tends to improve or resolve shortly after...
Decreased Body Temperature01:29

Decreased Body Temperature

A decreased body temperature can occur in patients with hypothermia and frostbite. Heat loss with extended cold exposure overpowers the body's ability to create heat, resulting in hypothermia. Core temperature readings help classify hypothermia. Mild hypothermia is temperatures between 32 °C (89.6 °F) and 35°C (95 °F) and is caused by impaired thermoregulation. Moderate hypothermia is temperatures between 28 C (82.4 °F) and 32 °C (89.6 °F) caused by sustained extreme cold exposure, and severe...
Hormonal Regulation of the Menstrual Cycle01:22

Hormonal Regulation of the Menstrual Cycle

The ovarian cycle regulates endometrial changes throughout a single menstrual cycle via the coordinated action of gonadotrophin-releasing hormone (GnRH) and gonadotrophins.
At puberty, GnRH begins a pulsatile release pattern, which triggers the anterior pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). The frequency and amplitude of GnRH pulses vary across the menstrual cycle, with faster pulses favoring LH release and slower pulses favoring FSH release.
Mitral Valve Prolapse II: Assessment and Management01:22

Mitral Valve Prolapse II: Assessment and Management

IntroductionA range of clinical features characterizes Mitral Valve Prolapse (MVP), but it is important to note that many individuals with MVP are asymptomatic and may remain so throughout their lives. For those who do exhibit symptoms, the following are the key clinical features:Palpitations: This is a common symptom where individuals feel an irregular or rapid heartbeat. Palpitations in MVP are often due to arrhythmias such as premature ventricular contractions or supraventricular tachycardia.
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption01:22

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption

As individuals age, their body's physiology evolves, affecting drug pharmacokinetics. The most apparent changes occur in the gastrointestinal tract, where an increase in gastric pH, a delay in gastric emptying, and a reduction in gastrointestinal motility are observed. Remarkably, these changes do not substantially modify the absorption of orally administered drugs, particularly those absorbed via passive diffusion.Transdermal drug delivery emerges as a highly viable method for older adults due...

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Heat-sensitive Moxibustion as a Traditional Chinese Medicine Therapy for Chronic Obstructive Pulmonary Disease Combined with Insomnia
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Persistent hot flushes in older postmenopausal women.

Alison J Huang1, Deborah Grady, Vanessa L Jacoby

  • 1Department of Medicine, University of California-San Francisco, USA. ahuang@ucsfmed.org

Archives of Internal Medicine
|April 30, 2008
PubMed
Summary

Hot flushes persist for many older postmenopausal women, impacting quality of life. Identifying risk factors like recent menopause and sleep issues can guide treatment for these persistent symptoms.

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Published on: August 13, 2019

Area of Science:

  • Gerontology
  • Women's Health
  • Menopause Research

Background:

  • Hot flushes are a common symptom experienced by postmenopausal women.
  • Understanding the long-term nature and predictors of hot flushes is crucial for managing women's health in later life.

Purpose of the Study:

  • To investigate the prevalence, natural history, and predictors of hot flushes in older postmenopausal women.
  • To identify factors associated with the onset and persistence of hot flushes.

Main Methods:

  • A questionnaire assessed hot flush prevalence, severity, and 3-year change in 3167 postmenopausal women with osteoporosis.
  • Logistic regression analysis identified characteristics linked to symptoms at baseline and follow-up.

Main Results:

  • At baseline, 11.8% of women reported bothersome hot flushes.
  • Predictors of baseline symptoms included lower education, recent menopause, prior estrogen use, hysterectomy, higher BMI, higher FSH, lower HDL, vaginal dryness, and sleep disturbances.
  • After 3 years, 56.5% of women with initial symptoms still experienced them, associated with fewer years since menopause and sleep difficulties.

Conclusions:

  • Hot flushes represent a persistent issue for a significant number of women into late postmenopause.
  • Identifying risk factors is key for guiding the evaluation and treatment of hot flushes in this demographic.