Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cryptococcal Meningitis01:27

Cryptococcal Meningitis

Cryptococcal meningitis is a life-threatening opportunistic infection predominantly associated with HIV/AIDS, accounting for over 100,000 deaths annually worldwide. However, it also affects individuals with other forms of immunosuppression, including those undergoing immunosuppressive therapy, organ transplant recipients, patients with innate immunodeficiencies, and individuals with hematological disorders. The infection is caused mainly by Cryptococcus neoformans and Cryptococcus gattii,...
Bacterial Meningitis I: Introduction01:22

Bacterial Meningitis I: Introduction

Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...
Bacterial Meningitis II: Pathophysiology01:26

Bacterial Meningitis II: Pathophysiology

Bacterial meningitis typically begins when pathogens such as Neisseria meningitidis and Streptococcus pneumoniae colonize the nasopharynx and invade the bloodstream. This process is facilitated by bacterial virulence factors, such as polysaccharide capsules, which resist phagocytosis and complement-mediated killing. Less commonly, bacteria reach the central nervous system via contiguous spread from infections like otitis media or sinusitis, through congenital or acquired dural defects, or...
Bacterial Meningitis01:24

Bacterial Meningitis

Bacterial meningitis is a severe infectious disease involving inflammation of the meninges, the protective membranes surrounding the brain and spinal cord. It occurs when pathogenic bacteria cross the blood–brain barrier and enter the cerebrospinal fluid. Common causative organisms include Neisseria meningitidis, Streptococcus pneumoniae, Haemophilus influenzae type b, Listeria monocytogenes, and Escherichia coli K1. The exact route of entry varies by pathogen and host condition.Routes of Entry...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Comparing the Level of Knowledge on External Ventricular Drain Care: A National Study of Neurosurgical and General ICU Nurses.

Nursing in critical care·2026
Same author

Upfront stereotactic radiosurgery for large posterior fossa metastases: a multicenter evaluation of clinical outcomes.

Journal of neuro-oncology·2026
Same author

Forewords to the Brain Trauma Foundation Guidelines for the Management of Penetrating Traumatic Brain Injury, Second Edition.

Neurosurgery·2026
Same author

Brain Trauma Foundation Guidelines for the Management of Penetrating Traumatic Brain Injury, Second Edition.

Neurosurgery·2026
Same author

Treatment Algorithms From the Brain Trauma Foundation Guidelines for the Management of Penetrating Traumatic Brain Injury, Second Edition.

Neurosurgery·2026
Same author

Empowering exhausted T cells of Glioblastoma patients by Neurotransmitters and Neuropeptides: decreasing immune checkpoint inhibitors, and increasing CD3zeta, proliferation and Glioblastoma arrest.

Cancer immunology, immunotherapy : CII·2026

Related Experiment Video

Updated: Jul 5, 2026

PET and MRI Guided Irradiation of a Glioblastoma Rat Model Using a Micro-irradiator
10:48

PET and MRI Guided Irradiation of a Glioblastoma Rat Model Using a Micro-irradiator

Published on: December 28, 2017

Radiation-induced meningioma.

Felix Umansky1, Yigal Shoshan, Guy Rosenthal

  • 1Department of Neurosurgery, Hadassah-Hebrew University Medical Center, Jerusalem, Israel. umansky@hadassah

Neurosurgical Focus
|May 2, 2008
PubMed
Summary

High doses of ionizing radiation, once thought safe for neural tissue, are now known to cause radiation-induced meningiomas (RIMs). This review details RIMs from childhood treatments, dental X-rays, and atomic bomb exposure.

More Related Videos

Translational Orthotopic Models of Glioblastoma Multiforme
07:37

Translational Orthotopic Models of Glioblastoma Multiforme

Published on: February 17, 2023

Related Experiment Videos

Last Updated: Jul 5, 2026

PET and MRI Guided Irradiation of a Glioblastoma Rat Model Using a Micro-irradiator
10:48

PET and MRI Guided Irradiation of a Glioblastoma Rat Model Using a Micro-irradiator

Published on: December 28, 2017

Translational Orthotopic Models of Glioblastoma Multiforme
07:37

Translational Orthotopic Models of Glioblastoma Multiforme

Published on: February 17, 2023

Area of Science:

  • Neurology
  • Oncology
  • Radiology

Background:

  • Historically, human neural tissue was considered resistant to radiation's carcinogenic effects.
  • High-dose diagnostic and therapeutic radiation exposures were common in the early-to-mid 20th century.
  • Delayed side effects of irradiation now include secondary central nervous system neoplasms.

Purpose of the Study:

  • To review the literature on radiation-induced meningiomas (RIMs).
  • To emphasize RIMs linked to childhood cancer/tinea capitis treatment, dental X-rays, and atomic bomb exposure.
  • To present incidence, natural history, and surgical management of RIMs.

Main Methods:

  • Literature review focusing on radiation-induced meningiomas.
  • Analysis of cases from childhood treatments, dental X-rays, and atomic bomb survivors.
  • Review of clinical experience in managing RIMs versus sporadic meningiomas.

Main Results:

  • Radiation-induced meningiomas (RIMs) are a known long-term side effect of irradiation.
  • RIMs arise from various exposures, including childhood therapeutic radiation and diagnostic dental X-rays.
  • The review covers RIM incidence, latency, histopathology, recurrence, and surgical considerations.

Conclusions:

  • Radiation-induced meningiomas are a significant delayed effect of ionizing radiation exposure.
  • Understanding RIMs' unique characteristics is crucial for diagnosis and management.
  • Surgical management of RIMs may differ from sporadic meningiomas.