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[Cardiovascular risk factors in chronic obstructive pulmonary disease: results of the ARCE study]
Pilar de Lucas-Ramos1, José Luis Izquierdo-Alonso, José Miguel Rodríguez-González Moro
1Servicio de Neumología, Hospital General Universitario Gregorio Marañón, Madrid, España. plucasr.hgugm@salud.madrid.org
Insights
Cardiovascular risk factors are highly prevalent in patients with chronic obstructive pulmonary disease (COPD). Cardiovascular disease prevalence in COPD patients exceeds general population rates, independent of disease severity.
Area of Science:
- Pulmonology
- Cardiology
- Epidemiology
Context:
- Cardiovascular disease (CVD) is a leading cause of mortality in patients with chronic obstructive pulmonary disease (COPD).
- The relationship between COPD and CVD is complex, with ongoing debate about whether traditional risk factors or COPD itself drives this comorbidity.
- Understanding this association is crucial for managing COPD patients effectively.
Purpose:
- To investigate the prevalence of cardiovascular risk factors and comorbidities in a community-based COPD population.
- To determine if COPD severity correlates with the presence of cardiovascular disease.
- To analyze the impact of traditional risk factors on cardiovascular health in COPD patients.
Summary:
- A cross-sectional study of 572 COPD patients revealed high rates of hypertension (53%), obesity (27%), dyslipidemia (26%), and diabetes (23%).
- Prevalence of ischemic heart disease (16.4%), cerebrovascular disease (7%), and peripheral vascular disease (17%) was significant.
- Cardiovascular comorbidity was not associated with COPD severity but showed a trend with age and traditional risk factors.
Impact:
- Cardiovascular risk factors are highly prevalent in COPD patients, contributing to increased comorbidity.
- The observed rates of cardiovascular and cerebrovascular disease surpass those in the general population.
- These findings underscore the need for proactive cardiovascular risk management in individuals with COPD, irrespective of airflow obstruction severity.
Objective:
Cardiovascular disease is a common cause of death in patients with chronic obstructive pulmonary disease (COPD). It is not clear whether the high cardiovascular comorbidity is due to an increase in traditional risk factors or whether, in contrast, COPD can be considered an independent risk factor. The aim of this study was to analyze the prevalence of risk factors and cardiovascular comorbidity in a community-based population treated for COPD.
Patients And Methods:
This was a concurrent multicenter, cross-sectional study that included 572 patients with confirmed diagnosis of COPD. Information on cardiovascular risk factors and comorbidity was collected by extracting data from the medical records of the participating center.
Results:
The mean (SD) forced expiratory volume in 1 second (FEV1) was 53.7% (16.85%) of predicted and the ratio of FEV1 to forced vital capacity was 57.9% (10.9%). Hypertension was reported in 53%, obesity in 27%, dyslipidemia in 26%, and diabetes in 23% of the patients. The prevalence of risk factors was not related to disease severity, but there was a trend towards an association with age. In the study group, 16.4% had ischemic heart disease, 7% cerebrovascular disease, and 17% peripheral vascular disease. Cardiovascular disease was not associated with COPD severity, but such an association was reported for age and traditional risk factors.
Conclusions:
Cardiovascular risk factors are highly prevalent in patients with COPD. The prevalence of cardiovascular and cerebrovascular disease exceeds that reported in the general population. No relationship was found between the severity of airflow obstruction and the presence of cardiovascular comorbidity.
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