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Production of Pseudotyped Particles to Study Highly Pathogenic Coronaviruses in a Biosafety Level 2 Setting
Published on: March 1, 2019
Development and characterization of an equine infectious anemia virus Env-pseudotyped reporter virus
R L Tallmadge1, M A Brindley, J Salmans
1Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, WA 99163, USA.
Clinical and Vaccine Immunology : CVI
|May 2, 2008
Abstract:
We developed a replication-defective reporter virus pseudotyped with the envelope glycoprotein of equine infectious anemia virus (EIAV). The in vitro host range and neutralization phenotype of EIAV Env-pseudotyped virus were similar to those of replication-competent virus. An EIAV Env pseudovirus will improve antigenic characterization of viral variants and evaluation of lentivirus vaccines.
