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Effects of delays in peripheral blood processing, including cryopreservation, on detection of CD31 expression on
Jeanette Higgins1, Julia A Metcalf, Randy A Stevens
1AIDS Monitoring Laboratory, Clinical Services Program, SAIC-Frederick, Inc, NCI Frederick, Frederick, Maryland 21702, USA.
Abstract:
Delayed processing of peripheral blood or peripheral blood mononuclear cell isolation and cryopreservation can lead to the detection of somewhat higher levels of CD31 expression on naïve CD4 T cells by flow cytometry. These observations should be considered in the planning of multicenter clinical trials and in the interpretation of the results of functional studies.
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