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Evaluation of Left Ventricular Structure and Function using 3D Echocardiography
Published on: October 28, 2020
Global left-ventricular function assessment using dual-source multidetector CT: effect of improved temporal
Michael Puesken1, Roman Fischbach, Mirja Wenker
1Department of Clinical Radiology, University Hospital of Muenster, Albert-Schweitzer-Strasse 33, 48149 Muenster, Germany.
European Radiology
|May 2, 2008
Summary
Dual-source CT (DSCT) accurately assesses global left-ventricular (LV) function, correlating well with cardiac MRI. Even with limited phases, DSCT is a reliable alternative for evaluating LV volumes and ejection fraction.
Area of Science:
- Cardiovascular Imaging
- Radiology
- Medical Physics
Background:
- Cardiac MRI is the gold standard for assessing global left-ventricular (LV) function.
- Multiphase dual-source CT (DSCT) offers potential for volumetric assessment, but its accuracy compared to MRI requires validation.
Purpose of the Study:
- To compare global LV function parameters derived from cine MRI with those obtained from multiphase DSCT.
- To evaluate the impact of different reconstruction phase intervals (5% vs. 10%) on DSCT-derived LV parameters.
Main Methods:
- Twenty-eight patients with suspected or known coronary artery disease (CAD) underwent DSCT coronary angiography.
- LV end-diastolic volume (EDV), end-systolic volume (ESV), stroke volume (SV), and ejection fraction (EF) were calculated from DSCT datasets reconstructed at 5% and 10% intervals.
- Cine MRI served as the reference standard for comparison.
Main Results:
- Threshold-based 3D segmentation was feasible for all DSCT datasets.
- DSCT underestimated EDV and ESV but showed excellent correlation with MRI (r=0.95/0.97).
- Reconstruction at 5% intervals, compared to 10%, altered phase detection and resulted in a minor, non-significant overestimation of LV EF by 1.9%.
Conclusions:
- Threshold-based 3D segmentation allows accurate and reliable DSCT determination of global LV function.
- DSCT is virtually interchangeable with cine MRI for LV function assessment, even with a limited number of reconstructed phases.
