Related Experiment Video
Updated: Jul 5, 2026

09:13
Testing Sensory and Multisensory Function in Children with Autism Spectrum Disorder
Published on: April 22, 2015
Regression, developmental trajectory and associated problems in disorders in the autism spectrum: the SNAP study
Gillian Baird1, Tony Charman, Andrew Pickles
1Newcomen Centre, Guy's & St. Thomas' NHS Foundation Trust, London, SE1 9RT, UK. gillian.baird@gstt.nhs.uk
Journal of Autism and Developmental Disorders
|May 2, 2008
Summary
Language regression occurred in 30% of children with autism spectrum disorder (ASD), but not in those without ASD. Regression correlated with increased autistic symptoms and altered developmental paths.
Area of Science:
- Developmental Psychology
- Neurodevelopmental Disorders
- Pediatric Neurology
Background:
- Autism Spectrum Disorder (ASD) is a complex neurodevelopmental condition.
- Understanding developmental trajectories and regression in children with ASD is crucial for early intervention.
- Previous research on regression in ASD has yielded varied findings.
Purpose of the Study:
- To determine the rates of language regression in children with autism spectrum disorder (ASD) and related neurodevelopmental conditions.
- To explore factors associated with regression in this population.
- To investigate the relationship between regression and other clinical features.
Main Methods:
- A population-derived cohort of 255 children aged 9-14 years with special educational needs was studied.
- Participants were categorized into narrowly defined autism, broader ASD, and non-ASD neurodevelopmental problems.
- Rates of language regression and associated clinical findings were analyzed.
Main Results:
- Language regression was reported in 30% of children with narrowly defined autism, 8% with broader ASD, and less than 3% in controls.
- Regression was linked to higher autistic symptom severity and deviations in developmental trajectory.
- No association was found between regression and epilepsy or gastrointestinal issues.
Conclusions:
- Language regression is a significant concern in a notable proportion of children with autism spectrum disorder.
- Regression appears to be associated with core autistic features and broader developmental changes.
- Further research is needed to understand the underlying mechanisms and implications of regression in ASD.
Related Concept Videos
Autism Spectrum Disorder
Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by persistent deficits in social communication and interaction alongside restrictive and repetitive behaviors or interests. ASD is sometimes accompanied by intellectual impairment.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
Modeling in Therapy
Modeling, a key technique in therapy, uses observational learning to help clients acquire and practice new skills by watching therapists demonstrate desired behaviors. This approach, rooted in Albert Bandura's concept of vicarious learning, plays a significant role in therapeutic interventions for various psychological conditions, including social anxiety, ADHD, and depression.
Participant Modeling
Participant modeling involves therapists demonstrating calm and effective behaviors in situations...
Participant Modeling
Participant modeling involves therapists demonstrating calm and effective behaviors in situations...
Attention-Deficit/Hyperactivity Disorder
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings.
Oppositional Defiant Disorder
A persistent pattern of angry or irritable mood, defiant behavior, or vindictiveness characterizes Oppositional Defiant Disorder (ODD). Symptoms must occur over at least six months, involve interactions with individuals beyond siblings, and meet specific diagnostic criteria to be clinically significant. The disorder affects emotional regulation, social interactions, and behavior, often manifesting early in life and influencing long-term development and functioning.
Diagnostic Criteria and...
Diagnostic Criteria and...
Conduct Disorder
Conduct disorder is a complex mental health diagnosis characterized by a repetitive and persistent pattern of behavior that violates societal norms, the rights of others, or age-appropriate rules. The diagnostic criteria for conduct disorder require the presence of at least three problematic behaviors within the past 12 months, with at least one occurring in the past six months. These behaviors are grouped into four categories: aggression toward people and animals; destruction of property;...
Social Anxiety Disorder
Social anxiety disorder, also known as social phobia, is characterized by an intense fear of social situations where one might face humiliation, rejection, embarrassment, or negative evaluation. This disorder leads individuals to avoid activities like casual conversations, public speaking, or seemingly simple tasks such as eating, signing documents, or swimming, in public settings. Its impact extends beyond discomfort, often significantly interfering with daily functioning and quality of life.
