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Related Concept Videos

Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
Pulmonary Function Tests01:25

Pulmonary Function Tests

Pulmonary Function Tests (PFTs)
Pulmonary Function Tests are crucial diagnostic tools for assessing respiratory function, particularly in patients with chronic respiratory disorders. They comprehensively evaluate lung volumes, ventilatory function, breathing mechanics, diffusion, and gas exchange. These tests help diagnose pulmonary diseases and play a significant role in monitoring disease progression, evaluating disability, and assessing response to therapy.
PFTs involve using a spirometer, a...
Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the progression...

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Related Experiment Video

Updated: Jul 5, 2026

A 3D Human Lung Tissue Model for Functional Studies on Mycobacterium tuberculosis Infection
10:10

A 3D Human Lung Tissue Model for Functional Studies on Mycobacterium tuberculosis Infection

Published on: October 5, 2015

[Pulmonary function in patients with focal pulmonary tuberculosis].

V B Nefedov, L A Popova, E A Shergina

    Problemy Tuberkuleza I Boleznei Legkikh
    |May 3, 2008
    PubMed
    Summary

    Focal pulmonary tuberculosis impacts lung function, causing changes in lung volumes and impaired gas exchange. These functional changes, while generally slight, indicate reduced bronchial patency and gas exchange efficiency in patients.

    Area of Science:

    • Pulmonary Medicine
    • Respiratory Physiology
    • Infectious Diseases

    Background:

    • Pulmonary tuberculosis (TB) is an infectious disease affecting lung function.
    • Understanding the specific functional changes in focal pulmonary TB is crucial for patient management.

    Purpose of the Study:

    • To assess lung volumes, capacities, bronchial patency, and gas exchange in patients with focal pulmonary TB.
    • To quantify the functional changes associated with focal pulmonary tuberculosis.

    Main Methods:

    • Pulmonary function tests were performed on 40 patients with focal pulmonary TB.
    • Measurements included vital capacity (VC), forced vital capacity (FVC), forced expiratory volume in 1 second (FEV1), diffusing capacity of the lungs for carbon monoxide (DLCO), and arterial blood gases (PaO2, PaCO2).

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    Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates
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    Published on: September 5, 2017

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    Last Updated: Jul 5, 2026

    A 3D Human Lung Tissue Model for Functional Studies on Mycobacterium tuberculosis Infection
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    Published on: October 5, 2015

    Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates
    10:04

    Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates

    Published on: September 5, 2017

    Main Results:

    • 75% of patients exhibited altered lung volumes and capacities, primarily increased total lung capacity (TGV) and pulmonary residual volume (PRV).
    • 57.5% showed impaired bronchial patency, indicated by reduced mid-expiratory flow rates (MEF50, MEF75) and FEV1/VC%.
    • 25% presented with pulmonary gas exchange dysfunction, marked by decreased DLCO-SB, PaO2, and PaCO2.

    Conclusions:

    • Focal pulmonary TB leads to measurable changes in lung volumes, bronchial patency, and gas exchange.
    • The observed functional impairments, though generally slight, highlight the need for monitoring respiratory health in TB patients.