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Updated: Jul 5, 2026

Semiconductor Sequencing for Preimplantation Genetic Testing for Aneuploidy
Published on: August 25, 2019
Ethics is an essential dimension of first-trimester risk assessment for trisomy 21
Frank A Chervenak1, Laurence B McCullough
1Department of Obstetrics and Gynecology, Weill Medical College of Cor nell University, New York, NY 10021, USA. fac2001@med.cornell.edu
Abstract:
We identify the clinical implications of the ethics of informed consent for risk assessment for trisomy 21. Based on the ethics of informed consent, we argue that routinely offering first-trimester risk assessment in centers qualified to provide it is ethically obligatory. We describe how pregnant women can be expected to respond to this offer. We then argue that routinely withholding the results of first-trimester risk assessment is ethically unjustified. The ethics of informed consent is an essential dimension of first-trimester risk assessment for trisomy 21.
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09:30Pre-Implantation Genetic Testing for Aneuploidy on a Semiconductor Based Next-Generation Sequencing Platform
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