Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Functional Outcome Prediction in Young Adults With Mental Health Symptoms Using Machine Learning and Large Language Models: Longitudinal Observational Study.

JMIR mental health·2026
Same author

Estimation of positron emission tomography amyloid load and related biomarkers in Alzheimer's disease using evoked potential tomography EEG: development and internal validation in a cross-sectional cohort.

Alzheimer's research & therapy·2026
Same author

Childhood maltreatment is linked to transdiagnostic age- and sex-specific cortical thinning and reduced amygdalar volume in young adults.

European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology·2026
Same author

Transcranial direct current stimulation (tDCS) as an additional treatment to cognitive behavior group therapy in adults with tobacco dependence - a double-blind, randomized, sham-controlled pilot trial.

Psychiatry research·2026
Same author

[Long-term treatment of severe depression].

Fortschritte der Neurologie-Psychiatrie·2026
Same author

Enhancing the understanding and clinical utility of P300 in psychotic disorders: the contribution of a bimodal oddball paradigm.

Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology·2026

Related Experiment Video

Updated: Jul 5, 2026

Reliable Acquisition of Electroencephalography Data during Simultaneous Electroencephalography and Functional MRI
11:00

Reliable Acquisition of Electroencephalography Data during Simultaneous Electroencephalography and Functional MRI

Published on: March 19, 2021

Simultaneous EEG-fMRI: perspectives in psychiatry.

Christoph Mulert1, Oliver Pogarell, Ulrich Hegerl

  • 1Department of Psychiatry, University of Munich, Germany. cmulert@med.uni-muenchen.de

Clinical EEG and Neuroscience
|May 3, 2008
PubMed
Summary

Neurophysiological studies reveal altered brain activity in psychiatric disorders. Integrating electroencephalography (EEG) and functional magnetic resonance imaging (fMRI) offers a powerful approach to precisely localize neural generators.

More Related Videos

Equipment Setup and Artifact Removal for Simultaneous Electroencephalogram and Functional Magnetic Resonance Imaging for Clinical Review in Epilepsy
10:23

Equipment Setup and Artifact Removal for Simultaneous Electroencephalogram and Functional Magnetic Resonance Imaging for Clinical Review in Epilepsy

Published on: June 23, 2023

Simultaneous fMRI and Electrophysiology in the Rodent Brain
08:22

Simultaneous fMRI and Electrophysiology in the Rodent Brain

Published on: August 19, 2010

Related Experiment Videos

Last Updated: Jul 5, 2026

Reliable Acquisition of Electroencephalography Data during Simultaneous Electroencephalography and Functional MRI
11:00

Reliable Acquisition of Electroencephalography Data during Simultaneous Electroencephalography and Functional MRI

Published on: March 19, 2021

Equipment Setup and Artifact Removal for Simultaneous Electroencephalogram and Functional Magnetic Resonance Imaging for Clinical Review in Epilepsy
10:23

Equipment Setup and Artifact Removal for Simultaneous Electroencephalogram and Functional Magnetic Resonance Imaging for Clinical Review in Epilepsy

Published on: June 23, 2023

Simultaneous fMRI and Electrophysiology in the Rodent Brain
08:22

Simultaneous fMRI and Electrophysiology in the Rodent Brain

Published on: August 19, 2010

Area of Science:

  • Neuroscience
  • Psychiatry
  • Biological Psychiatry

Background:

  • Robust neurophysiological findings, like reduced P300 potential amplitudes in schizophrenia, are well-established in biological psychiatry.
  • Decades of research show abnormal central processing in psychiatric diseases, but precise localization of neural generators remains a challenge.
  • Different neural generator configurations can yield identical electroencephalography (EEG) activity, hindering accurate localization of event-related potentials.

Purpose of the Study:

  • To review the physiology, methodology, and applications of integrating electroencephalography (EEG) and functional magnetic resonance imaging (fMRI) in psychiatry.
  • To address the challenge of precisely localizing neural generators of brain activity in psychiatric disorders.
  • To highlight the potential of combined EEG-fMRI for a deeper understanding of brain function.

Main Methods:

  • Review of existing literature on neurophysiological findings in psychiatric diseases.
  • Discussion of the limitations of traditional EEG for precise neural generator localization.
  • Exploration of functional magnetic resonance imaging (fMRI) for hemodynamic changes and its limitations in capturing rapid neural activity.
  • Focus on the integration of simultaneous EEG and fMRI measurements.

Main Results:

  • While functional magnetic resonance imaging (fMRI) excels at localization based on hemodynamic changes, it cannot differentiate rapid neural activity like oscillation modes.
  • Electroencephalography (EEG) measures neural electrical activity but struggles with precise source localization due to signal superposition.
  • Simultaneous EEG-fMRI integration overcomes the limitations of each individual technique, offering enhanced spatiotemporal resolution.

Conclusions:

  • The integration of simultaneous electroencephalography (EEG) and functional magnetic resonance imaging (fMRI) is a critical methodological advancement.
  • Combined EEG-fMRI provides a more comprehensive understanding of brain activity dynamics in psychiatric research.
  • This integrated approach holds significant promise for advancing our knowledge of the neural underpinnings of psychiatric disorders.