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Updated: Jul 5, 2026

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A Mouse Distraction Osteogenesis Model
Published on: November 14, 2018
Treatment of a mandibular cleft using distraction
Marguerite Grossman1, Stuart Super
1Department of Oral and Maxillofacial Surgery, Lenox Hill Hospital, New York, NY, USA. amgos@yahoo.com
The New York State Dental Journal
|May 3, 2008
Summary
Distraction osteogenesis offers a new way to fix mandibular hypoplasia. This study shows its use in a patient with this condition and a cleft mandible.
Area of Science:
- Oral and Maxillofacial Surgery
- Orthodontics
- Regenerative Medicine
Background:
- Mandibular hypoplasia presents significant challenges in facial reconstruction.
- Congenital conditions like cleft mandible can exacerbate mandibular hypoplasia.
- Distraction osteogenesis is an emerging technique for skeletal reconstruction.
Observation:
- The study focuses on a patient diagnosed with mandibular hypoplasia.
- The patient also has a documented history of a mandibular cleft.
- Mandibular distraction was the chosen intervention for this case.
Findings:
- Successful application of distraction osteogenesis in correcting mandibular hypoplasia.
- Demonstrated efficacy in a complex case involving a cleft mandible.
- Achieved significant bone lengthening and improved mandibular morphology.
Implications:
- Distraction osteogenesis is a viable and effective treatment for complex mandibular hypoplasia.
- This technique offers a valuable alternative to traditional surgical methods.
- Further research into distraction osteogenesis for craniofacial anomalies is warranted.

